Evidence map›Paper›PMID 37375454›Full record

ArticlePathogens (Basel, Switzerland)2023

Analysis of CRISPR/Cas Genetic Structure, Spacer Content and Molecular Epidemiology in Brazilian

Adrianne M A Silva, Ana C O Luz, Keyla V M Xavier, Maria P S Barros, Hirisleide B Alves, Marcus V A Batista, Tereza C Leal-Balbino

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Adrianne M A SilvaDepartamento de Microbiologia, Instituto Aggeu Magalhães, Fundação Oswaldo Cruz, Recife CEP 50740-465, Pernambuco, Brazil.
Ana C O LuzDepartamento de Microbiologia, Instituto Aggeu Magalhães, Fundação Oswaldo Cruz, Recife CEP 50740-465, Pernambuco, Brazil.
Keyla V M XavierDepartamento de Microbiologia, Instituto Aggeu Magalhães, Fundação Oswaldo Cruz, Recife CEP 50740-465, Pernambuco, Brazil.
Maria P S BarrosLaboratório de Bioprocessos, Centro de Tecnologias Estratégicas do Nordeste, Recife CEP 50740-545, Pernambuco, Brazil.
Hirisleide B AlvesDepartamento de Microbiologia, Instituto Aggeu Magalhães, Fundação Oswaldo Cruz, Recife CEP 50740-465, Pernambuco, Brazil.
Marcus V A BatistaLaboratório de Genética Molecular e Biotecnologia, Centro de Ciências Biológicas e da Saúde-CCBS, Universidade Federal de Sergipe, Aracaju CEP 49060-108, Sergipe, Brazil.ORCID 0000-0003-4745-8919
Tereza C Leal-BalbinoDepartamento de Microbiologia, Instituto Aggeu Magalhães, Fundação Oswaldo Cruz, Recife CEP 50740-465, Pernambuco, Brazil.ORCID 0000-0001-7151-3514
Fundação Oswaldo Cruz · BRCentro de Tecnologias Estratégicas do Nordeste · BRUniversidade Federal de Sergipe · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CRISPR/Cas is a molecular mechanism to prevent predatory viruses from invading bacteria via the insertion of small viral sequences (spacers) in its repetitive locus. The nature of spacer incorporation and the viral origins of spacers provide an overview of the genetic evolution of bacteria, their natural viral predators, and the mechanisms that prokaryotes may use to protect themselves, or to acquire mobile genetic elements such as plasmids. Here, we report on the CRISPR/Cas genetic structure, its spacer content, and strain epidemiology through MLST and CRISPR typing in

Indexed as

CRISPR/Casmolecular epidemiologyphagespacer

Identifiers

PMID37375454
PMCPMC10302819
OpenAlexW4378575697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.