ArticlePathogens (Basel, Switzerland)2023
Molecular Characterization of Porcine Reproductive and Respiratory Syndrome Virus in Korea from 2018 to 2022.
Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- Growth performance and immune responses of pigs from nursery to grower-finisher phase following different PRRSV-2 vaccination strategies: Evidence supporting a prime-boost regimen under field conditions in Korea.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2026Article
- PRRSV Fetal Infection in Pigs as a Risk Factor for the Emergence of More Efficient Zoonotic Hosts for Swine-Origin Influenza Virus.Veterinary sciences · 2026Article
- A Lipid Nanoparticle-Formulated GP5-mRNA Vaccine Induces PRRSV-Specific Humoral and Cellular Immune Responses in BALB/c Mice.Veterinary sciences · 2026Article
- Genetic and Respiratory Pathogenic Comparison of Two PRRSV-2 Isolates Classified as Lineage Korean A and B.Transboundary and emerging diseases · 2026Article
- Development of a novel duplex crystal digital PCR for the detection of PRRSV-1 and PRRSV-2.Frontiers in cellular and infection microbiology · 2026Article
- The first report of porcine parvovirus 8 detection and genetic analysis in South Korea.Frontiers in veterinary science · 2026Article
- Nationwide emergence and spread of highly virulent PRRSV-2 mutants in Korea.Porcine health management · 2025Article
- In Silico Designed Multi-Epitope Vaccine Based on the Conserved Fragments in Viral Proteins for Broad-Spectrum Protection Against Porcine Reproductive and Respiratory Syndrome Virus.Veterinary sciences · 2025Article
- Nextclade data set for the ORF5-based lineage classification of PRRSV-1.Microbiology resource announcements · 2025Article
- Porcine Reproductive and Respiratory Syndrome Virus Prevalence and Pathogenicity of One NADC34-like Virus Isolate Circulating in China.Microorganisms · 2025Article
- Validation of Polymorphisms Associated with the Immune Response After Vaccination Against Porcine Reproductive and Respiratory Syndrome Virus in Yorkshire Gilts.Veterinary sciences · 2025Article
- Lineage 7 Porcine Reproductive and Respiratory Syndrome Vaccine Demonstrates Cross-Protection Against Lineage 1 and Lineage 3 Strains.Vaccines · 2025Article
- Prevalence of four infectious diseases (Porcine Circovirus Type 2, Aujeszky's Disease, Porcine Reproductive and Respiratory Syndrome, Mycoplasma hyopneumoniae) in wild boars in South Korea.The Journal of veterinary medical science · 2025Article
- Metagenomic detection and genome assembly of novel PRRSV-2 strain using Oxford Nanopore Flongle flow cell.Journal of animal science · 2025Article
- Immunopathological features of highly pathogenic Korean Lineage B PRRSV-2: insights into virulence indicators and host immune responses.Frontiers in immunology · 2025Article
- Comparative Genomic and Biological Investigation of NADC30- and NADC34-Like PRRSV Strains Isolated in South Korea.Transboundary and emerging diseases · 2025Article
- Reproductive Pathogenic Characteristics of a Highly Virulent Porcine Reproductive and Respiratory Syndrome Virus L1J (Lineage Korean Clade C) in Gilts.Transboundary and emerging diseases · 2025Article
- Reproductive efficacy of a modified-live porcine reproductive and respiratory syndrome vaccine against Korean PRRSV-2 challenge in sows.Frontiers in veterinary science · 2025Article
- Assessment of PRRSV and PCV2 seroprevalence and antigen prevalence in minipigs at laboratory-animal production facilities.Journal of advanced veterinary and animal research · 2024Article
- Porcine reproductive and respiratory syndrome developments: An in-depth review of recent findings.Open veterinary journal · 2024Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Porcine reproductive and respiratory syndrome (PRRS) is an endemic disease in the Republic of Korea. Surveillance of PRRS virus (PRRSV) types is critical to tailor control measures. This study collected 5062 serum and tissue samples between 2018 and 2022. Open reading frame 5 (ORF5) sequences suggest that subgroup A (42%) was predominant, followed by lineage 1 (21%), lineage 5 (14%), lineage Korea C (LKC) (9%), lineage Korea B (LKB) (6%), and subtype 1C (5%). Highly virulent lineages 1 (NADC30/34/MN184) and 8 were also detected. These viruses typically mutate or recombine with other viruses. ORF5 and non-structural protein 2 (NSP2) deletion patterns were less variable in the PRRSV-1. Several strains belonging to PRRSV-2 showed differences in NSP2 deletion and ORF5 sequences. Similar vaccine-like isolates to the PRRSV-1 subtype 1C and PRRSV-2 lineage 5 were also found. The virus is evolving independently in the field and has eluded vaccine protection. The current vaccine that is used in Korea offers only modest or limited heterologous protection. Ongoing surveillance to identify the current virus strain in circulation is necessary to design a vaccine. A systemic immunization program with region-specific vaccinations and stringent biosecurity measures is required to reduce PRRSV infections in the Republic of Korea.
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Registered trials
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