Evidence map›Paper›PMID 37375415›Full record

ReviewMolecules (Basel, Switzerland)2023

A Comprehensive Update of Various Attempts by Medicinal Chemists to Combat COVID-19 through Natural Products.

Ayesha Rafiq, Tooba Jabeen, Sana Aslam, Matloob Ahmad, Usman Ali Ashfaq, Noor Ul Amin Mohsin, Magdi E A Zaki, Sami A Al-Hussain

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Viruses · 2024
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Ayesha RafiqDepartment of Chemistry, Government College University, Faisalabad 38000, Pakistan.
Tooba JabeenDepartment of Chemistry, Government College University, Faisalabad 38000, Pakistan.
Sana AslamDepartment of Chemistry, Government College Women University, Faisalabad 38000, Pakistan.
Matloob AhmadDepartment of Chemistry, Government College University, Faisalabad 38000, Pakistan.ORCID 0000-0003-1302-8056
Usman Ali AshfaqDepartment of Bioinformatics and Biotechnology, Government College University, Faisalabad 38000, Pakistan.ORCID 0000-0002-5495-805X
Noor Ul Amin MohsinDepartment of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad 38000, Pakistan.
Magdi E A ZakiDepartment of Chemistry, Faculty of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia.ORCID 0000-0002-5643-9202
Sami A Al-HussainDepartment of Chemistry, Faculty of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia.
Government College University, Faisalabad · PKImam Mohammad ibn Saud Islamic University · SAGovernment College Women University Faisalabad · PK

Funding

Government College University, Faisalabad MA-Chem-TTSImam Muhammad ibn Saud Islamic University IMSIU Grant No. 21-13-18-067
6 · The paper itself

Abstract

The ongoing COVID-19 pandemic has resulted in a global panic because of its continual evolution and recurring spikes. This serious malignancy is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the outbreak, millions of people have been affected from December 2019 till now, which has led to a great surge in finding treatments. Despite trying to handle the pandemic with the repurposing of some drugs, such as chloroquine, hydroxychloroquine, remdesivir, lopinavir, ivermectin, etc., against COVID-19, the SARS-CoV-2 virus continues its out-of-control spread. There is a dire need to identify a new regimen of natural products to combat the deadly viral disease. This article deals with the literature reports to date of natural products showing inhibitory activity towards SARS-CoV-2 through different approaches, such as in vivo, in vitro, and in silico studies. Natural compounds targeting the proteins of SARS-CoV-2-the main protease (M

Indexed as

Biological ProductsCOVID-19Antiviral AgentsHumansMolecular Docking SimulationPandemicsSARS-CoV-2Antiviral AgentsBiological ProductsCOVID-19in silicoin vitroin vivomolecular dockingmolecular docking simulationsnatural productsSARS-CoV-2

Identifiers

PMID37375415
PMCPMC10305344
OpenAlexW4381337739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.