Evidence map›Paper›PMID 37375326›Full record

ArticleMolecules (Basel, Switzerland)2023

Synthesis and Receptor Binding Studies of α5 GABA

Dishary Sharmin, Md Yeunus Mian, Michael Marcotte, Thomas D Prevot, Etienne Sibille, Jeffrey M Witkin, James M Cook

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Dishary SharminDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin Milwaukee, Milwaukee, WI 53201, USA.
Md Yeunus MianDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin Milwaukee, Milwaukee, WI 53201, USA.
Michael MarcotteCampbell Family Mental Health Research Institute of CAMH, Toronto, ON M5S 2S1, Canada.
Thomas D PrevotCampbell Family Mental Health Research Institute of CAMH, Toronto, ON M5S 2S1, Canada.ORCID 0000-0002-6774-603X
Etienne SibilleCampbell Family Mental Health Research Institute of CAMH, Toronto, ON M5S 2S1, Canada.
Jeffrey M WitkinDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin Milwaukee, Milwaukee, WI 53201, USA.
James M CookDepartment of Chemistry and Biochemistry, Milwaukee Institute of Drug Discovery, University of Wisconsin Milwaukee, Milwaukee, WI 53201, USA.ORCID 0000-0001-5512-3022
University of Wisconsin–Milwaukee · USUniversity of Toronto · CAMental Health Research Canada · CASt. Vincent Hospital · US

Funding

Tolerance and Physical Dependence after Chronic Benzodiazepine TreatmentR01DA043204 · NIDA · UNIVERSITY OF MISSISSIPPI MED CTR · PI JAMES K ROWLETT · 2017 to 2026
$4.3M
Benzodiazepine Choice and Polydrug UseR01DA054177 · NIDA · UNIVERSITY OF MISSISSIPPI MED CTR · PI Sally L Huskinson · 2022 to 2026
$2.5M
GABA-A receptor subtype mechanisms and the abuse-related effects of alcoholR01AA029023 · NIAAA · UNIVERSITY OF MISSISSIPPI MED CTR · PI PLATT, DONNA M · 2020 to 2024
$2.4M
NIAAA NIH HHS R01 AA029023NIDA NIH HHS R01 DA043204NIDA NIH HHS R01 DA054177
6 · The paper itself

Abstract

GABA mediates inhibitory actions through various GABA

Indexed as

Cognitive DysfunctionReceptors, GABA-AAnimalsBenzodiazepinesGABA-A Receptor Agonistsgamma-Aminobutyric AcidHumansLigandsBenzodiazepinesGABA-A Receptor Agonistsgamma-Aminobutyric AcidLigandsReceptors, GABA-Acognitive disordersimidazodiazepineoff-target profilePDSPpositive allosteric modulatorγ-Aminobutyric acid (GABA)

Identifiers

PMID37375326
PMCPMC10303271
OpenAlexW4380997693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.