Evidence map›Paper›PMID 37375315›Full record

ArticleMolecules (Basel, Switzerland)2023

Dual Anta-Inhibitors Targeting Protein Kinase CK1δ and A

Beatrice Francucci, Simone Angeloni, Diego Dal Ben, Catia Lambertucci, Massimo Ricciutelli, Andrea Spinaci, Aleksei Smirnov, Rosaria Volpini, Michela Buccioni, Gabriella Marucci

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Beatrice FrancucciMedicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Simone AngeloniMedicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0001-6571-2242
Diego Dal BenMedicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0002-6616-6885
Catia LambertucciMedicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0003-2004-1531
Massimo RicciutelliMedicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Andrea SpinaciMedicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0002-5172-651X
Aleksei SmirnovMedicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0003-0045-9631
Rosaria VolpiniMedicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0002-5304-5232
Michela BuccioniMedicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0002-8383-0813
Gabriella MarucciMedicinal Chemistry Unit, School of Pharmacy, University of Camerino, 62032 Camerino, Italy.
Università di Camerino · IT

Funding

Italian Ministry of University and Research, PRIN 2017 2017MT3993_004.
6 · The paper itself

Abstract

Currently, the number of patients with neurodegenerative pathologies is estimated at over one million, with consequences also on the economic level. Several factors contribute to their development, including overexpression of A

Indexed as

Casein Kinase IdeltaNeurodegenerative DiseasesHumansReceptor, Adenosine A2AReceptors, Purinergic P1Up-RegulationCasein Kinase IdeltaReceptor, Adenosine A2AReceptors, Purinergic P1A2AAR antagonistsA2A/CK1δ dual inhibitorsCK1δ inhibitorscytokineneuroinflammationneuroprotection

Identifiers

PMID37375315
PMCPMC10302146
OpenAlexW4380997634

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.