Evidence map›Paper›PMID 37375242›Full record

ArticleMolecules (Basel, Switzerland)2023

Amphotericin B-Silver Hybrid Nanoparticles Help to Unveil the Mechanism of Biological Activity of the Antibiotic: Disintegration of Cell Membranes.

Sebastian Janik, Ewa Grela, Sylwia Stączek, Agnieszka Zdybicka-Barabas, Rafal Luchowski, Wieslaw I Gruszecki, Wojciech Grudzinski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sebastian JanikDepartment of Biophysics, Institute of Physics, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.
Ewa GrelaDepartment of Biophysics, Institute of Physics, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.ORCID 0000-0002-1667-6780
Sylwia StączekDepartment of Immunobiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.ORCID 0000-0002-4879-1329
Agnieszka Zdybicka-BarabasDepartment of Immunobiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.ORCID 0000-0003-3146-3836
Rafal LuchowskiDepartment of Biophysics, Institute of Physics, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.ORCID 0000-0003-1156-8059
Wieslaw I GruszeckiDepartment of Biophysics, Institute of Physics, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.ORCID 0000-0002-8245-3913
Wojciech GrudzinskiDepartment of Biophysics, Institute of Physics, Maria Curie-Sklodowska University, 20-031 Lublin, Poland.ORCID 0000-0002-8825-1423

Funding

National Science Center 2019/33/B/NZ7/00902
6 · The paper itself

Abstract

Amphotericin B is a popular antifungal antibiotic, and despite decades of pharmacological application, the exact mode of its biological activity is still a matter of debate. Amphotericin B-silver hybrid nanoparticles (AmB-Ag) have been reported to be an extremely effective form of this antibiotic to combat fungi. Here, we analyze the interaction of AmB-Ag with

Indexed as

Amphotericin BNanoparticlesAnti-Bacterial AgentsAntifungal AgentsCandida albicansCell MembraneSilverAmphotericin BAnti-Bacterial AgentsAntifungal AgentsSilveramphotericin Bfungal infectionsnanomedicinenanoparticles

Identifiers

PMID37375242
PMCPMC10301372

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.