Evidence map›Paper›PMID 37375032›Full record

ArticleMicroorganisms2023

Amelioration of Murine Colitis by Attenuated

Shih-Yao Chen, Chun-Ting Chu, Mei-Lin Yang, Jian-Da Lin, Chung-Teng Wang, Che-Hsin Lee, I-Chen Lin, Ai-Li Shiau, Pin Ling, Chao-Liang Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Shih-Yao ChenDepartment of Nursing, College of Nursing, Chung Hwa University of Medical Technology, Tainan 71703, Taiwan.ORCID 0000-0003-4929-855X
Chun-Ting ChuDivision of Colorectal Surgery, Department of Surgery, Ditmanson Medical Foundation Chia-Yi Christian Hospital, 539, Zhongxiao Road, Chiayi City 60002, Taiwan.
Mei-Lin YangDitmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi City 60002, Taiwan.
Jian-Da LinDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.ORCID 0000-0003-3697-4766
Chung-Teng WangDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
Che-Hsin LeeDepartment of Biological Sciences, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.ORCID 0000-0002-8543-3862
I-Chen LinDivision of Colorectal Surgery, Department of Surgery, Ditmanson Medical Foundation Chia-Yi Christian Hospital, 539, Zhongxiao Road, Chiayi City 60002, Taiwan.
Ai-Li ShiauDitmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi City 60002, Taiwan.ORCID 0000-0003-2449-8547
Pin LingDepartment of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
Chao-Liang WuDitmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi City 60002, Taiwan.ORCID 0000-0001-7821-9406
Chia-Yi Christian Hospital · TWNational Cheng Kung University · TWChung Hwa University of Medical Technology · TWNational Sun Yat-sen University · TWNational Taiwan University · TW

Funding

Ditmanson Medical Foundation Chia-Yi Christian Hospital, and National Cheng Kung University NCKUCYC-P-11101-2National Science and Technology Council Taiwan MOST 109-2314-B-006-086National Science and Technology Council Taiwan MOST 110-2314-B-705-002National Science and Technology Council Taiwan NSTC 111-2314-B-705-002
6 · The paper itself

Abstract

The imbalance of mucosal immunity in the lower gastrointestinal tract can lead to chronic inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis. IBD is a chronic inflammatory disorder that causes small and/or large intestines ulceration. According to previous studies, recombinant interleukin (IL)-10 protein and genetically modified bacteria secreting IL-10 ameliorate dextran sulfate sodium (DSS)-induced colitis in mice. IL-19 is a transcriptional activator of IL-10 and can alter the balance of T helper 1 (Th)1/Th2 cells in favor of Th2. In this study, we aimed to investigate whether the expression of the murine IL-19 gene carried by

Indexed as

dextran sulfate sodium-induced colitisinflammatory bowel diseasesinterleukin-19Salmonella choleraesuis

Identifiers

PMID37375032
PMCPMC10304794
OpenAlexW4380078948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.