Evidence map›Paper›PMID 37374986›Full record

ArticleMicroorganisms2023

Compositional Variations between Adult and Infant Skin Microbiome: An Update.

Barry Murphy, Michael Hoptroff, David Arnold, Andrew Cawley, Emily Smith, Suzanne E Adams, Alex Mitchell, Malcolm J Horsburgh, Joanne Hunt, Bivash Dasgupta and 4 more

Abstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Microbiome dysbiosis and therapeutic restoration in atopic dermatitis.Frontiers in cellular and infection microbiology · 2026
    Review
  2. Review
  3. Skin Care Practices in Indian Newborns and Infants: Current Scenario.Pediatric health, medicine and therapeutics · 2025
    Review
  4. Pattern Recognition by NOD-Like Receptors.Advances in experimental medicine and biology · 2025
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Barry MurphyUnilever Research & Development, Port Sunlight, Bebington, Wirral CH63 3JW, UK.ORCID 0000-0003-2305-5875
Michael HoptroffUnilever Research & Development, Port Sunlight, Bebington, Wirral CH63 3JW, UK.ORCID 0000-0003-4437-6221
David ArnoldUnilever Research & Development, Port Sunlight, Bebington, Wirral CH63 3JW, UK.
Andrew CawleyUnilever Research & Development, Port Sunlight, Bebington, Wirral CH63 3JW, UK.
Emily SmithUnilever Research & Development, Port Sunlight, Bebington, Wirral CH63 3JW, UK.ORCID 0000-0001-6601-0533
Suzanne E AdamsUnilever Research & Development, Port Sunlight, Bebington, Wirral CH63 3JW, UK.
Alex MitchellEagle Genomics, Wellcome Genome Campus, Hinxton, Cambridge CB10 1DR, UK.
Malcolm J HorsburghInstitute of Infection Biology, Veterinary and Ecological Sciences, University of Liverpool, Liverpool L69 7ZB, UK.ORCID 0000-0002-3806-0039
Joanne HuntUnilever Research & Development, Port Sunlight, Bebington, Wirral CH63 3JW, UK.
Bivash DasguptaUnilever, 40 Merritt Blvd, Trumbull, CT 06611, USA.
Naresh GhatliaUnilever, 40 Merritt Blvd, Trumbull, CT 06611, USA.
Samantha SamarasUnilever, 40 Merritt Blvd, Trumbull, CT 06611, USA.
Ashely MacGuire-FlanaganUnilever, 40 Merritt Blvd, Trumbull, CT 06611, USA.
Kirti SharmaUnilever, North Rocks Road, North Rocks, NSW 2151, Australia.ORCID 0000-0001-7857-1004

Funding

Unilever (United Kingdom) NA
6 · The paper itself

Abstract

Human skin and its commensal microbiome form the first layer of protection to the outside world. A dynamic microbial ecosystem of bacteria, fungi and viruses, with the potential to respond to external insult, the skin microbiome has been shown to evolve over the life course with an alteration in taxonomic composition responding to altered microenvironmental conditions on human skin. This work sought to investigate the taxonomic, diversity and functional differences between infant and adult leg skin microbiomes. A 16S rRNA gene-based metataxonomic analysis revealed significant differences between the infant and adult skin groups, highlighting differential microbiome profiles at both the genus and species level. Diversity analysis reveals differences in the overall community structure and associated differential predicted functional profiles between the infant and adult skin microbiome suggest differing metabolic processes are present between the groups. These data add to the available information on the dynamic nature of skin microbiome during the life course and highlight the predicted differential microbial metabolic process that exists on infant and adult skin, which may have an impact on the future design and use of cosmetic products that are produced to work in consort with the skin microbiome.

Indexed as

adultfunctioninfantmicrobiomenetworksskin

Identifiers

PMID37374986
PMCPMC10304506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.