Evidence map›Paper›PMID 37374973›Full record

ArticleMicroorganisms2023

Oral Microbiome Traits of Type 1 Diabetes and Phenylketonuria Patients in Latvia.

Iveta Abola, Dita Gudra, Maija Ustinova, Davids Fridmanis, Darta Elizabete Emulina, Ingus Skadins, Anda Brinkmane, Una Lauga-Tunina, Linda Gailite, Madara Auzenbaha

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Iveta AbolaScientific Laboratory of Molecular Genetics, Rīga Stradiņš University, LV-1007 Riga, Latvia.
Dita GudraLatvian Biomedical Research and Study Centre, LV-1067 Riga, Latvia.ORCID 0000-0002-9446-4521
Maija UstinovaLatvian Biomedical Research and Study Centre, LV-1067 Riga, Latvia.ORCID 0000-0001-7882-397X
Davids FridmanisLatvian Biomedical Research and Study Centre, LV-1067 Riga, Latvia.ORCID 0000-0003-0310-0448
Darta Elizabete EmulinaScientific Laboratory of Molecular Genetics, Rīga Stradiņš University, LV-1007 Riga, Latvia.
Ingus SkadinsScientific Laboratory of Molecular Genetics, Rīga Stradiņš University, LV-1007 Riga, Latvia.ORCID 0000-0003-4044-8750
Anda BrinkmaneDepartment of Conservative Dentistry and Oral Health, Rīga Stradiņš University, LV-1007 Riga, Latvia.
Una Lauga-TuninaDepartment of Endocrinology, Children's Clinical University Hospital, LV-1004 Riga, Latvia.
Linda GailiteScientific Laboratory of Molecular Genetics, Rīga Stradiņš University, LV-1007 Riga, Latvia.ORCID 0000-0002-7219-1294
Madara AuzenbahaScientific Laboratory of Molecular Genetics, Rīga Stradiņš University, LV-1007 Riga, Latvia.ORCID 0000-0002-9925-2376
Riga Stradiņš University · LVLatvian Biomedical Research and Study Centre · LVChildren's Clinical University Hospital · LV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some metabolic disorder treatments require patients to follow a specific diet or to consume supplements that, over time, can lead to oral microbiome alterations. Well-known disorders requiring such treatment are phenylketonuria (PKU), an inborn error of amino acid metabolism, and type 1 diabetes (T1D), a metabolic disorder that requires a specific diet regimen. Therefore, the aim of this study was to investigate the oral health and microbiome characteristics that might contribute to caries activity and periodontal disease risk in PKU and T1D patients. In this cross-sectional study, 45 PKU patients, 24 T1D patients, and 61 healthy individuals between the ages of 12 and 53 years were examined. Their anamnestic data and dental status were assessed by one dentist. Microbial communities were detected from saliva-isolated DNA using

Indexed as

16S rRNA sequencingmicrobiomephenylketonuriatype 1 diabetes

Identifiers

PMID37374973
PMCPMC10300800
OpenAlexW4379055797

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.