Evidence map›Paper›PMID 37374928›Full record

ArticleMicroorganisms2023

Saliva Decreases Sucrose-Induced Cariogenicity in an Experimental Biological Caries Model.

Rodrigo A Giacaman, Rodrigo Umaña, María José Nuñez, Natalia Díaz-Garrido, Constanza Echeverría, Natalia García-Manríquez, Alex Mira, Constanza E Fernández, Karla Gambetta-Tessini, Carla P Lozano

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Rodrigo A GiacamanCariology Unit, Department of Oral Rehabilitation, Faculty of Dentistry, University of Talca, Talca 3462227, Chile.ORCID 0000-0003-3362-5173
Rodrigo UmañaCariology Unit, Department of Oral Rehabilitation, Faculty of Dentistry, University of Talca, Talca 3462227, Chile.
María José NuñezCariology Unit, Department of Oral Rehabilitation, Faculty of Dentistry, University of Talca, Talca 3462227, Chile.
Natalia Díaz-GarridoCariology Unit, Department of Oral Rehabilitation, Faculty of Dentistry, University of Talca, Talca 3462227, Chile.ORCID 0000-0003-1220-015X
Constanza EcheverríaCariology Unit, Department of Oral Rehabilitation, Faculty of Dentistry, University of Talca, Talca 3462227, Chile.
Natalia García-ManríquezCariology Unit, Department of Oral Rehabilitation, Faculty of Dentistry, University of Talca, Talca 3462227, Chile.
Alex MiraGenomics and Health Department, Foundation for the Promotion of Health and Biomedical Research (FISABIO), 46020 Valencia, Spain.ORCID 0000-0002-9127-3877
Constanza E FernándezCariology Unit, Department of Oral Rehabilitation, Faculty of Dentistry, University of Talca, Talca 3462227, Chile.
Karla Gambetta-TessiniCariology Unit, Department of Oral Rehabilitation, Faculty of Dentistry, University of Talca, Talca 3462227, Chile.
Carla P LozanoLaboratory of Biochemistry and Oral Biology, Institute for Research in Dental Sciences, Faculty of Dentistry, University of Chile, Santiago 8330111, Chile.ORCID 0000-0002-1294-3677
University of Talca · CLFundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana · ESUniversity of Chile · CL

Funding

Agencia Nacional de Investigación y Desarrollo Fondecyt 1210188
6 · The paper itself

Abstract

objectiveWhether a minimum quantity of saliva inhibit the caries process remains uncertain. This study aimed to investigate the impact of saliva dilutions on an in vitro caries model using

methods

resultsIn both enamel and dentin, an inverse relationship was observed between acidogenicity, demineralization, and the proportion of saliva. Even small quantities of saliva incorporated into the media led to a noticeable reduction in enamel and dentin demineralization. Saliva presence resulted in significant reductions in biomass, viable

conclusionsHigh quantities of saliva can almost completely inhibit sucrose-induced cariogenicity, while even small amounts exhibit a dose-dependent caries-protective effect.

Indexed as

biofilmcariescariogenicitysalivaStreptococcus mutans

Identifiers

PMID37374928
PMCPMC10304388
OpenAlexW4378717767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.