Evidence map›Paper›PMID 37374908›Full record

ArticleMicroorganisms2023

A Pilot Cross-Sectional Study of Immunological and Microbiome Profiling Reveals Distinct Inflammatory Profiles for Smokers, Electronic Cigarette Users, and Never-Smokers.

Peter G Shields, Kevin L Ying, Theodore M Brasky, Jo L Freudenheim, Zihai Li, Joseph P McElroy, Sarah A Reisinger, Min-Ae Song, Daniel Y Weng, Mark D Wewers and 3 more

Abstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. E-Cigarette Use, Cigarette Smoking, and Sex Are Associated With Nasal Microbiome Dysbiosis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Peter G ShieldsComprehensive Cancer Center, The Ohio State University and James Cancer Hospital, Columbus, OH 43210, USA.ORCID 0000-0002-7404-217X
Kevin L YingComprehensive Cancer Center, The Ohio State University and James Cancer Hospital, Columbus, OH 43210, USA.ORCID 0000-0003-4640-5452
Theodore M BraskyComprehensive Cancer Center, The Ohio State University and James Cancer Hospital, Columbus, OH 43210, USA.ORCID 0000-0001-7781-609X
Jo L FreudenheimDepartment of Epidemiology and Environmental Health, University at Buffalo, Buffalo, NY 14261, USA.ORCID 0000-0002-9301-0499
Zihai LiComprehensive Cancer Center, The Ohio State University and James Cancer Hospital, Columbus, OH 43210, USA.
Joseph P McElroyComprehensive Cancer Center, The Ohio State University and James Cancer Hospital, Columbus, OH 43210, USA.ORCID 0000-0003-0366-1210
Sarah A ReisingerComprehensive Cancer Center, The Ohio State University and James Cancer Hospital, Columbus, OH 43210, USA.ORCID 0000-0002-3076-5405
Min-Ae SongDivision of Environmental Health Sciences, College of Public Health, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-2864-0224
Daniel Y WengComprehensive Cancer Center, The Ohio State University and James Cancer Hospital, Columbus, OH 43210, USA.ORCID 0000-0003-2734-5626
Mark D WewersPulmonary and Critical Care Medicine, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-7079-5633
Noah B WhitemanComprehensive Cancer Center, The Ohio State University and James Cancer Hospital, Columbus, OH 43210, USA.ORCID 0000-0003-3629-0671
Yiping YangComprehensive Cancer Center, The Ohio State University and James Cancer Hospital, Columbus, OH 43210, USA.
Ewy A MathéComprehensive Cancer Center, The Ohio State University and James Cancer Hospital, Columbus, OH 43210, USA.ORCID 0000-0003-4491-8107

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Daniel G. Stover · 1985 to 2026
$132.3M
The Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6M
Project 4: Comprehension of Health Risks in More and Less Arousing Affe p240-275P50CA180908 · NCI · OHIO STATE UNIVERSITY · PI SHIELDS, PETER G., WEWERS, MARY ELLEN · 2013 to 2017
$18.9M
Informatics Research CoreZICTR000410 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI MATHÉ, EWY · 2021 to 2025
$11.7M
Regulation of tumor-infiltrating T cells by macrophagesR01CA260858 · NCI · OHIO STATE UNIVERSITY · PI HUANG, XIAOPEI · 2021 to 2025
$2.2M
Mitochondrial Genetic Alterations: A clinical trial of a standardized research e-cigaretteR21HL147401 · NHLBI · OHIO STATE UNIVERSITY · PI SONG, MIN-AE · 2019 to 2020
$429k
Intramural NIH HHS ZIC TR000410NCATS NIH HHS UL1 TR001070NCI NIH HHS P30 CA016058NCI NIH HHS P50 CA180908NCI NIH HHS P50CA180908NCI NIH HHS R01 CA260858NHLBI NIH HHS R21 HL147401
6 · The paper itself

Abstract

Smokers (SM) have increased lung immune cell counts and inflammatory gene expression compared to electronic cigarette (EC) users and never-smokers (NS). The objective of this study is to further assess associations for SM and EC lung microbiomes with immune cell subtypes and inflammatory gene expression in samples obtained by bronchoscopy and bronchoalveolar lavage (

Indexed as

bronchoalveolar lavageinflammationmetatranscriptomeRNA-sequencingvaping

Identifiers

PMID37374908
PMCPMC10303504

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.