Evidence map›Paper›PMID 37374901›Full record

ArticleMicroorganisms2023

PHERI-Phage Host ExploRation Pipeline.

Andrej Baláž, Michal Kajsik, Jaroslav Budiš, Tomáš Szemes, Ján Turňa

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. In Vitro Susceptibility of Clinical and Carrier Strains ofInternational journal of molecular sciences · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Microorganisms · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Andrej BalážGeneton Ltd., Ilkovicova 8, 841 04 Bratislava, Slovakia.
Michal KajsikScience Park, Comenius University, Ilkovicova 8, 841 04 Bratislava, Slovakia.ORCID 0000-0002-1605-3591
Jaroslav BudišGeneton Ltd., Ilkovicova 8, 841 04 Bratislava, Slovakia.ORCID 0000-0002-8667-6655
Tomáš SzemesGeneton Ltd., Ilkovicova 8, 841 04 Bratislava, Slovakia.
Ján TurňaScience Park, Comenius University, Ilkovicova 8, 841 04 Bratislava, Slovakia.
Geneton (Slovakia) · SKComenius University Bratislava · SKMedirex Group Academy · SK

Funding

Operational Program Integrated Infrastructure 313011ATR9
6 · The paper itself

Abstract

Antibiotic resistance is becoming a common problem in medicine, food, and industry, with multidrug-resistant bacterial strains occurring in all regions. One of the possible future solutions is the use of bacteriophages. Phages are the most abundant form of life in the biosphere, so we can highly likely purify a specific phage against each target bacterium. The identification and consistent characterization of individual phages was a common form of phage work and included determining bacteriophages' host-specificity. With the advent of new modern sequencing methods, there was a problem with the detailed characterization of phages in the environment identified by metagenome analysis. The solution to this problem may be to use a bioinformatic approach in the form of prediction software capable of determining a bacterial host based on the phage whole-genome sequence. The result of our research is the machine learning algorithm-based tool called PHERI. PHERI predicts the suitable bacterial host genus for the purification of individual viruses from different samples. In addition, it can identify and highlight protein sequences that are important for host selection.

Indexed as

bacteriophagesmachine learning algorithmphage host determination

Identifiers

PMID37374901
PMCPMC10305434
OpenAlexW4378378017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.