Evidence map›Paper›PMID 37374282›Full record

ArticleMedicina (Kaunas, Lithuania)2023

Design and Synthesis of New 4-(3,4,5-Trimethoxyphenyl)Thiazole-Pyrimidine Derivatives as Potential Antiproliferative Agents.

Ashraf K El-Damasy, Heewon Jin, Mohamed A Sabry, Hyun Ji Kim, Mohammed M Alanazi, Seon Hee Seo, Eun-Kyoung Bang, Gyochang Keum

Open access · goldAbstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Ashraf K El-DamasyCenter for Brain Technology, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.ORCID 0000-0002-8446-0383
Heewon JinCenter for Brain Technology, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Mohamed A SabryDepartment of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Hyun Ji KimCenter for Brain Technology, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.ORCID 0000-0002-7680-8773
Mohammed M AlanaziDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-0483-8113
Seon Hee SeoCenter for Brain Disorders, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Eun-Kyoung BangCenter for Brain Technology, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Gyochang KeumCenter for Brain Technology, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.ORCID 0000-0001-8767-8022
Korea Institute of Brain Science · KRMansoura University · EGKing Saud University · SA

Funding

Researchers Supporting Project number (RSPD2023R628), King Saud University, Riyadh, Saudi Arabia. (RSPD2023R628)the Institutional Program grant by the Korea Institute of Science and Technology [2E32212]the Korea Research Fellowship (KRF) Program grant through the National Research Foundation of Korea (NRF), funded by the Ministry of Science and ICT 2019H1D3A1A01070882the National Research Council of Science & Technology (NST) grant by the Korean government (MSIT) CAP-20-01-KRIBB
6 · The paper itself

Abstract

A new series of 3,4,5-trimethoxyphenyl thiazole pyrimidines has been synthesized and biologically evaluated for its in vitro anticancer activity. Compounds

Indexed as

Antineoplastic AgentsThiazolesCell Line, TumorCell ProliferationDose-Response Relationship, DrugDrug Screening Assays, AntitumorHumansPyrimidinesStructure-Activity RelationshipAntineoplastic AgentsPyrimidinesThiazolesADME-Tox predictionNCI-60 screeningNSCL cancer cell linepyrimidinesthiazoletrimethoxyphenyl

Identifiers

PMID37374282
PMCPMC10303439
OpenAlexW4379473169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.