Evidence map›Paper›PMID 37374170›Full record

ArticleLife (Basel, Switzerland)2023

Hip and Knee Osteoarthritis in Patients with Chronic Myeloproliferative Neoplasms: A Cross-Sectional Study.

Hrvoje Holik, Ivan Krečak, Marko Lucijanić, Ivan Samardžić, Danijel Pilipac, Ivana Vučinić Ljubičić, Božena Coha, Alma Kitter Pipić, Blaženka Miškić, Silva Zupančić-Šalek

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Hrvoje HolikDepartment of Internal Medicine, Dr. Josip Benčević General Hospital, 35000 Slavonski Brod, Croatia.
Ivan KrečakDepartment of Internal Medicine, General Hospital of Šibenik-Knin County, 22000 Šibenik, Croatia.
Marko LucijanićUniversity Hospital Dubrava, 10000 Zagreb, Croatia.ORCID 0000-0002-1372-2040
Ivan SamardžićDepartment of Orthopaedic Surgery, Dr. Josip Benčević General Hospital, 35000 Slavonski Brod, Croatia.
Danijel PilipacDepartment of Orthopaedic Surgery, General Hospital of Šibenik-Knin County, 22000 Šibenik, Croatia.
Ivana Vučinić LjubičićDepartment of Internal Medicine, Dr. Josip Benčević General Hospital, 35000 Slavonski Brod, Croatia.
Božena CohaDepartment of Internal Medicine, Dr. Josip Benčević General Hospital, 35000 Slavonski Brod, Croatia.
Alma Kitter PipićDepartment of Laboratory Diagnostics, General Hospital 'Dr Josip Benčević', 35000 Slavonski Brod, Croatia.
Blaženka MiškićDepartment of Internal Medicine, Dr. Josip Benčević General Hospital, 35000 Slavonski Brod, Croatia.
Silva Zupančić-ŠalekDepartment of Hematology and Coagulation, University Hospital Holy Spirit, 10000 Zagreb, Croatia.
University of Slavonski Brod · HRŠibenik University of Applied Sciences · HRUniversity of Rijeka · HRUniversity of Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoarthritis (OA) is a progressive degenerative disease with an inflammatory background. Chronic myeloproliferative neoplasms (MPN) are clonal hematopoietic disorders characterized by chronic inflammation and a tendency for connective tissue remodeling.

aimThis study aimed to investigate the prevalence and associated risk factors of symptomatic OA (sOA) in MPN patients. PATIENTS AND

methodsA total of 100 consecutive MPN (39 essential-thrombocythemia, 34 polycythemia-vera, 27 myelofibrosis) patients treated in two community hematologic centers were cross-sectionally evaluated. Patients were required to have both symptoms attributable to hip and/or knee OA and radiographic confirmation to be considered as having sOA.

resultsThe prevalence of hip and/or knee sOA was significantly higher among MPN patients than the previously reported prevalence in the general population of similar age (61% vs. 22%,

conclusionsThe prevalence of sOA in MPN patients was higher than that in the general population and seems to correlate with older age, increased myeloproliferation and a higher inflammatory state. Whether cytoreductive treatment may postpone OA development in MPN patients warrants additional confirmation.

Indexed as

bone paincytoreductive treatmentJAK2-V617Fmyeloproliferative neoplasmsosteoarthritis

Identifiers

PMID37374170
PMCPMC10300951
OpenAlexW4380997715

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.