Evidence map›Paper›PMID 37374160›Full record

ArticleLife (Basel, Switzerland)2023

A Cross-Sectional Study of Bone Nanomechanics in Hip Fracture and Aging.

Richard Stavri, Tabitha Tay, Crispin C Wiles, Erica Di Federico, Oliver Boughton, Shaocheng Ma, Angelo Karunaratne, John H Churchwell, Rajarshi Bhattacharya, Nicholas J Terrill and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Richard StavriMSk Laboratory, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London W6 8PR, UK.ORCID 0000-0002-5466-0982
Tabitha TayMSk Laboratory, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London W6 8PR, UK.
Crispin C WilesWarwick Medical School, University of Warwick, Coventry CV4 7AL, UK.ORCID 0000-0001-5860-3910
Erica Di FedericoDepartment of Bioengineering, Faculty of Engineering, Imperial College London, London SW7 2AZ, UK.
Oliver BoughtonMSk Laboratory, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London W6 8PR, UK.
Shaocheng MaDepartment of Mechanical Engineering, Faculty of Engineering, Imperial College London, London SW7 2AZ, UK.
Angelo KarunaratneDepartment of Mechanical Engineering, Faculty of Engineering, University of Moratuwa, Moratuwa 10400, Sri Lanka.
John H ChurchwellDepartment of Medical Physics and Biomedical Engineering, University College London, London WCIE 6BT, UK.
Rajarshi BhattacharyaSt. Mary's Hospital, Northwest London Major Trauma Centre, Imperial College London, London W2 1NY, UK.
Nicholas J TerrillDiamond Light Source Ltd., Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.ORCID 0000-0002-8783-1282
Justin P CobbMSk Laboratory, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London W6 8PR, UK.
Ulrich HansenDepartment of Mechanical Engineering, Faculty of Engineering, Imperial College London, London SW7 2AZ, UK.
Richard L AbelMSk Laboratory, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London W6 8PR, UK.
Imperial College London · GBDiamond Light Source · GBSt Mary's Hospital · GBUniversity College London · GBUniversity of Moratuwa · LKUniversity of Warwick · GB

Funding

Diamond Light Source Beamtime I22 SM13337Diamond Light Source Beamtime I22 SM17664The Royal Osteoporosis Society Grant Ref: 402
6 · The paper itself

Abstract

Bone mechanics is well understood at every length scale except the nano-level. We aimed to investigate the relationship between bone nanoscale and tissue-level mechanics experimentally. We tested two hypotheses: (1) nanoscale strains were lower in hip fracture patients versus controls, and (2) nanoscale mineral and fibril strains were inversely correlated with aging and fracture. A cross-sectional sample of trabecular bone sections was prepared from the proximal femora of two human donor groups (aged 44-94 years): an aging non-fracture control group (

Indexed as

agingbiomechanicsbone healthhip fracturenanomechanics

Identifiers

PMID37374160
PMCPMC10302642
OpenAlexW4380485807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.