Evidence map›Paper›PMID 37374091›Full record

ReviewLife (Basel, Switzerland)2023

Vitamin Effects in Primary Dysmenorrhea.

Alkis Matsas, Athanasios Sachinidis, Malamatenia Lamprinou, Eleni Stamoula, Panagiotis Christopoulos

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06339918 (Combined Effects of Kegel Exercises and 4-7-8 Breathing Technique on Pain Intensity, Symptom Severity and Functional Activity in Primary Dysmenorrhea), which is not on this map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06339918 nacompletednot on this mapstarted 2024, after this paper: background citation

Combined Effects of Kegel Exercises and 4-7-8 Breathing Technique on Pain Intensity, Symptom Severity and Functional Activity in Primary Dysmenorrhea

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2024Enrolled28ConditionsPrimary DysmenorrheaArmsKegelExercise, 4-7-8 breathing technique
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Alkis MatsasSecond Department of Obstetrics and Gynaecology, Medical School, "Aretaieion'' University Hospital, National and Kapodistrian University of Athens, 115 27 Athens, Greece.ORCID 0000-0002-9758-8079
Athanasios SachinidisFourth Department of Internal Medicine, Hippokration General Hospital of Thessaloniki, School of Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.ORCID 0000-0002-3309-6032
Malamatenia LamprinouLaboratory of Clinical Pharmacology, School of Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Eleni StamoulaDepartment of Biotechnology, Centre of Systems Biology, Biomedical Research Foundation of the Academy of Athens, 115 27 Athens, Greece.ORCID 0000-0002-8952-821X
Panagiotis ChristopoulosSecond Department of Obstetrics and Gynaecology, Medical School, "Aretaieion'' University Hospital, National and Kapodistrian University of Athens, 115 27 Athens, Greece.ORCID 0000-0003-4112-8396
Aristotle University of Thessaloniki · GRNational and Kapodistrian University of Athens · GRBiomedical Research Foundation of the Academy of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary dysmenorrhea is considered to be one of the most common gynecological complaints, affecting women's daily activities and social life. The severity of dysmenorrhea varies among women, and its management is of high importance for them. Given that non-steroidal anti-inflammatory drugs (NSAIDs), the established treatment for dysmenorrhea, are associated with many adverse events, alternative therapeutic options are under evaluation. Emerging evidence correlates management of dysmenorrhea with micronutrients, especially vitamins. PURPOSE: The aim of this narrative review is to highlight and provide evidence of the potential benefits of vitamins for the management of dysmenorrhea.

methodsThe articles were searched on PubMed, Scopus and Google Scholar. The searching process was based on keywords, such as "primary dysmenorrhea", "vitamins", "supplementation", "vitamin D", "vitamin E" and others. Our search focused on data derived from clinical trials, published only during the last decade (older articles were excluded).

resultsIn this review, 13 clinical trials were investigated. Most of them supported the anti-inflammatory, antioxidant and analgesic properties of vitamins. Particularly, vitamins D and E revealed a desirable effect on dysmenorrhea relief Conclusion: Despite the scarcity and heterogeneity of related research, the studies indicate a role of vitamins for the management of primary dysmenorrhea, proposing that they should be considered as alternative therapeutic candidates for clinical use. Nevertheless, this correlation warrants further research.

Indexed as

dysmenorrheavitamin B1vitamin Dvitamin Evitamin Kvitamins

Identifiers

PMID37374091
PMCPMC10303710
OpenAlexW4378983127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.