Evidence map›Paper›PMID 37374074›Full record

ReviewLife (Basel, Switzerland)2023

Deciphering Lung Adenocarcinoma Heterogeneity: An Overview of Pathological and Clinical Features of Rare Subtypes.

Andrea Mogavero, Paolo Bironzo, Luisella Righi, Alessandra Merlini, Federica Benso, Silvia Novello, Francesco Passiglia

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Recent advances in diagnostic and therapeutic approaches for pulmonary enteric adenocarcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Andrea MogaveroDepartment of Oncology, University of Turin, San Luigi Gonzaga Hospital, 10043 Orbassano, Italy.ORCID 0000-0001-8718-6773
Paolo BironzoDepartment of Oncology, University of Turin, San Luigi Gonzaga Hospital, 10043 Orbassano, Italy.ORCID 0000-0002-2784-5076
Luisella RighiDepartment of Oncology, University of Turin, San Luigi Gonzaga Hospital, 10043 Orbassano, Italy.ORCID 0000-0002-8927-204X
Alessandra MerliniDepartment of Oncology, University of Turin, San Luigi Gonzaga Hospital, 10043 Orbassano, Italy.
Federica BensoDepartment of Oncology, University of Turin, San Luigi Gonzaga Hospital, 10043 Orbassano, Italy.
Silvia NovelloDepartment of Oncology, University of Turin, San Luigi Gonzaga Hospital, 10043 Orbassano, Italy.
Francesco PassigliaDepartment of Oncology, University of Turin, San Luigi Gonzaga Hospital, 10043 Orbassano, Italy.
Ospedale San Luigi Gonzaga · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is one of the most frequently diagnosed cancers worldwide and the leading cause of cancer-related death. The 2021 World Health Organization (WHO) classification provided a detailed and updated categorization of lung adenocarcinomas with a special focus on rare histological types, including enteric, fetal and colloid types, as well as not otherwise specified adenocarcinoma, overall accounting for about 5-10% of all cases. However, rare entities are nowadays difficult to diagnose in most centers, and evidence of optimal therapeutic management for these patients is still lacking. In recent years, increasing knowledge about the mutational profile of lung cancer, in addition to the spreading diffusion of next-generation sequencing (NGS) in different centers, have been helpful in the identification of rare variants of lung cancer. Hence, the hope is that several new drugs will be available in the near future to treat these rare lung tumors, such as in targeted therapy and immunotherapy, which are often used in clinical practice for several malignancies. The aim of this review is to summarize the current knowledge about the molecular pathology and clinical management of the most common rare adenocarcinoma subtypes in order to provide a concise and updated report that can drive clinicians' choices in their routine practice.

Indexed as

colloid carcinomacolorectal cancerfetal carcinomaimmunochemistrymutation analysesNOS carcinomapulmonary enteric carcinoma

Identifiers

PMID37374074
PMCPMC10302096
OpenAlexW4378902419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.