Evidence map›Paper›PMID 37374052›Full record

ArticleLife (Basel, Switzerland)2023

The Polymorphisms in

Milos Petrovic, Tatjana Simic, Tatjana Djukic, Tanja Radic, Ana Savic-Radojevic, Milica Zekovic, Otas Durutovic, Aleksandar Janicic, Bogomir Milojevic, Boris Kajmakovic and 4 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. International journal of molecular sciences · 2025
    Article
  3. Glutathione-Dependent Pathways in Cancer Cells.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Milos PetrovicClinic of Urology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0002-9490-1197
Tatjana SimicInstitute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0001-8683-5129
Tatjana DjukicInstitute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0003-1959-5115
Tanja RadicInstitute of Mental Health, 11000 Belgrade, Serbia.
Ana Savic-RadojevicInstitute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0002-2026-4180
Milica ZekovicCentre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, National Institute of Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0003-2597-3426
Otas DurutovicClinic of Urology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Aleksandar JanicicClinic of Urology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Bogomir MilojevicClinic of Urology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0001-6784-8389
Boris KajmakovicClinic of Urology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0001-5335-1830
Marko ZivkovicClinic of Urology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Nebojsa BojanicClinic of Urology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Uros BumbasirevicClinic of Urology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0003-0367-2745
Vesna CoricInstitute of Medical and Clinical Biochemistry, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0003-0227-821X
University of Belgrade · RSInstitute of Mental Health · RSSerbian Academy of Sciences and Arts · RS

Funding

Wellcome Trust 200110
6 · The paper itself

Abstract

Members of the omega class of glutathione transferases (GSTs), GSTO1, and GSTO2, catalyze a range of reduction reactions as a part of the antioxidant defense system. Polymorphisms of genes encoding antioxidant proteins and the resultant altered redox profile have already been associated with the increased risk for testicular germ cell cancer (GCT) development. The aim of this pilot study was to assess the individual, combined, haplotype, and cumulative effect of

Indexed as

gene polymorphismglutathione transferaseGSTOoxidative stresstesticular GCT

Identifiers

PMID37374052
PMCPMC10301167
OpenAlexW4378575503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.