Evidence map›Paper›PMID 37374025›Full record

ReviewLife (Basel, Switzerland)2023

Tensins in Kidney Function and Diseases.

Chien-Wei Huang, Su Hao Lo

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Chien-Wei HuangDepartment of Biochemistry and Molecular Medicine, School of Medicine, University of California-Davis, Sacramento, CA 95817, USA.ORCID 0000-0001-5753-9654
Su Hao LoDepartment of Biochemistry and Molecular Medicine, School of Medicine, University of California-Davis, Sacramento, CA 95817, USA.
National Yang Ming Chiao Tung University · TWUniversity of California, Davis · US

Funding

Role of Cten in Prostate CancerR01CA102537 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI LO, SU HAO · 2004 to 2016
$2.4M
Roles of endothelial tensinsR01HL139473 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LO, SU HAO · 2018 to 2021
$1.6M
The Promoter or A Prostate Specific Gene, CtenR21DK064111 · NIDDK · UNIVERSITY OF CALIFORNIA DAVIS · PI LO, SU HAO · 2003 to 2004
$297k
Role of Cten in Prostate CancerR56CA102537 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LO, SU HAO · 2009 to 2009
$240k
NCI NIH HHS R01 CA102537NCI NIH HHS R56 CA102537NHLBI NIH HHS R01 HL139473NIDDK NIH HHS R21 DK064111NIH HHS CA102537NIH HHS DK64111NIH HHS HL139473
6 · The paper itself

Abstract

Tensins are focal adhesion proteins that regulate various biological processes, such as mechanical sensing, cell adhesion, migration, invasion, and proliferation, through their multiple binding activities that transduce critical signals across the plasma membrane. When these molecular interactions and/or mediated signaling are disrupted, cellular activities and tissue functions are compromised, leading to disease development. Here, we focus on the significance of the tensin family in renal function and diseases. The expression pattern of each tensin in the kidney, their roles in chronic kidney diseases, renal cell carcinoma, and their potentials as prognostic markers and/or therapeutic targets are discussed in this review.

Indexed as

cancerCTENcystic kidneyfocal adhesionnephrotic syndrometensin

Identifiers

PMID37374025
PMCPMC10305691
OpenAlexW4378229163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.