Evidence map›Paper›PMID 37373935›Full record

ReviewJournal of personalized medicine2023

Enhancing Radiotherapy Workflow for Head and Neck Cancer with Artificial Intelligence: A Systematic Review.

Ciro Franzese, Damiano Dei, Nicola Lambri, Maria Ausilia Teriaca, Marco Badalamenti, Leonardo Crespi, Stefano Tomatis, Daniele Loiacono, Pietro Mancosu, Marta Scorsetti

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Head and Neck Gross Tumor Volume Automatic Segmentation Using PocketNet.Head and Neck Tumor Segmentation for MR-Guided Applications : First MICCAI Challenge, HNTS-MRG 2024, held in conjunction with MICCAI 2024, Marrakesh, Morocco, October 17, 2024, proceedings · 2025
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Ciro FranzeseDepartment of Biomedical Sciences, Humanitas University, via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.ORCID 0000-0001-6893-6284
Damiano DeiDepartment of Biomedical Sciences, Humanitas University, via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.ORCID 0000-0001-9873-7868
Nicola LambriDepartment of Biomedical Sciences, Humanitas University, via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.ORCID 0000-0001-8706-6480
Maria Ausilia TeriacaIRCCS Humanitas Research Hospital, Radiotherapy and Radiosurgery Department, via Manzoni 56, Rozzano, 20089 Milan, Italy.
Marco BadalamentiIRCCS Humanitas Research Hospital, Radiotherapy and Radiosurgery Department, via Manzoni 56, Rozzano, 20089 Milan, Italy.
Leonardo CrespiDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, 20133 Milan, Italy.
Stefano TomatisIRCCS Humanitas Research Hospital, Radiotherapy and Radiosurgery Department, via Manzoni 56, Rozzano, 20089 Milan, Italy.
Daniele LoiaconoDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, 20133 Milan, Italy.ORCID 0000-0002-5355-0634
Pietro MancosuIRCCS Humanitas Research Hospital, Radiotherapy and Radiosurgery Department, via Manzoni 56, Rozzano, 20089 Milan, Italy.ORCID 0000-0002-0165-7931
Marta ScorsettiDepartment of Biomedical Sciences, Humanitas University, via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.
Humanitas University · ITIRCCS Humanitas Research Hospital · ITHuman Technopole · ITPolitecnico di Milano · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHead and neck cancer (HNC) is characterized by complex-shaped tumors and numerous organs at risk (OARs), inducing challenging radiotherapy (RT) planning, optimization, and delivery. In this review, we provided a thorough description of the applications of artificial intelligence (AI) tools in the HNC RT process.

methodsThe PubMed database was queried, and a total of 168 articles (2016-2022) were screened by a group of experts in radiation oncology. The group selected 62 articles, which were subdivided into three categories, representing the whole RT workflow: (i) target and OAR contouring, (ii) planning, and (iii) delivery.

resultsThe majority of the selected studies focused on the OARs segmentation process. Overall, the performance of AI models was evaluated using standard metrics, while limited research was found on how the introduction of AI could impact clinical outcomes. Additionally, papers usually lacked information about the confidence level associated with the predictions made by the AI models.

conclusionsAI represents a promising tool to automate the RT workflow for the complex field of HNC treatment. To ensure that the development of AI technologies in RT is effectively aligned with clinical needs, we suggest conducting future studies within interdisciplinary groups, including clinicians and computer scientists.

Indexed as

artificial intelligence (AI)automationdeep learning (DL)head and neck cancer (HNC)machine learning (ML)radiotherapy (RT)

Identifiers

PMID37373935
PMCPMC10301548
OpenAlexW4379230932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.