Evidence map›Paper›PMID 37373808›Full record

ArticleJournal of clinical medicine2023

Global Longitudinal Strain Predicts Outcomes in Patients with Reduced Left Ventricular Function Undergoing Transcatheter Edge-to-Edge Mitral Repair.

Estefania Fernandez-Peregrina, Luis Asmarats, Rodrigo Estevez-Loureiro, Isaac Pascual, Diana Bastidas, Tomas Benito-González, Berenice Caneiro-Queija, Pablo Avanzas, Jose Alberto De Agustin, Felipe Fernández-Vazquez and 10 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Estefania Fernandez-PeregrinaCardiology Unit, Interventional Cardiology Department, Hospital de la Santa Creu I Sant Pau, 08025 Barcelona, Spain.ORCID 0000-0002-3025-8251
Luis AsmaratsCardiology Unit, Interventional Cardiology Department, Hospital de la Santa Creu I Sant Pau, 08025 Barcelona, Spain.
Rodrigo Estevez-LoureiroInterventional Cardiology Unit, Hospital Alvaro Cunqueiro, 36312 Vigo, Spain.
Isaac PascualHeart Area, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.ORCID 0000-0001-5433-1364
Diana BastidasCardiovascular Institute, Hospital Clinico San Carlos, IdISSC, 28040 Madrid, Spain.
Tomas Benito-GonzálezDepartment of Cardiology, University Hospital of Leon, 24008 Leon, Spain.ORCID 0000-0002-8428-9248
Berenice Caneiro-QueijaInterventional Cardiology Unit, Hospital Alvaro Cunqueiro, 36312 Vigo, Spain.
Pablo AvanzasHeart Area, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.ORCID 0000-0002-4958-6108
Jose Alberto De AgustinCardiovascular Institute, Hospital Clinico San Carlos, IdISSC, 28040 Madrid, Spain.ORCID 0000-0002-4444-9622
Felipe Fernández-VazquezDepartment of Cardiology, University Hospital of Leon, 24008 Leon, Spain.ORCID 0000-0001-7187-1290
Manuel Barreiro-PérezInterventional Cardiology Unit, Hospital Alvaro Cunqueiro, 36312 Vigo, Spain.ORCID 0000-0001-7489-2935
Victor LeonHeart Area, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.ORCID 0000-0002-0173-6744
Luis Nombela-FrancoCardiovascular Institute, Hospital Clinico San Carlos, IdISSC, 28040 Madrid, Spain.
Carmen GarroteDepartment of Cardiology, University Hospital of Leon, 24008 Leon, Spain.
Chi-Hion LiCardiology Unit, Interventional Cardiology Department, Hospital de la Santa Creu I Sant Pau, 08025 Barcelona, Spain.ORCID 0000-0001-7556-3711
José Antonio BazInterventional Cardiology Unit, Hospital Alvaro Cunqueiro, 36312 Vigo, Spain.
Antonio AdebaHeart Area, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.ORCID 0000-0001-8890-946X
Jordi Sans-RosellóDepartment of Cardiology, Parc Taulí Hospital Universitari, 08208 Sabadell, Spain.ORCID 0000-0003-3176-6191
Javier GualisDepartment of Cardiology, University Hospital of Leon, 24008 Leon, Spain.ORCID 0000-0002-3680-6431
Dabit ArzamendiCardiology Unit, Interventional Cardiology Department, Hospital de la Santa Creu I Sant Pau, 08025 Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe timing and selection of optimal candidates for mitral transcatheter edge-to-edge valve repair remains to be fully determined, especially in cases with severely depressed left ventricular ejection fraction (LVEF). The objective of this study is to evaluate the prognostic value of myocardial strain (LVGLS) in this setting.

methodsRetrospectively, 172 consecutive patients with LVEF ≤40% and severe MR treated with MitraClip were included. Four groups were generated according to the LVEF (<30% or

resultsProcedural success was high (96.5%) and complications were rare. At one-year follow-up, 82.5% of patients maintained MR grade ≤2, 79.2% were at a NYHA class ≤II and a reduction of 80% in heart failure admissions was observed in all groups. Interestingly, among patients with a more depressed LVEF, LVGLS was found to be an independent predictor for cardiovascular mortality (HR: 3.3; 95% CI: 1.1-10,

conclusionsMitral valve repair with MitraClip is safe and it improves the mid-term functional class of patients regardless of LVEF. LVGLS can help in the selection of optimal candidates and timing for this procedure, as well as in the recognition of those patients with worse prognoses.

Indexed as

left ventricular global longitudinal strainMitraClipMitral regurgitation

Identifiers

PMID37373808
PMCPMC10298909

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.