Evidence map›Paper›PMID 37373755›Full record

ReviewJournal of clinical medicine2023

Varicocele: To Treat or Not to Treat?

Antonio Franco, Flavia Proietti, Veronica Palombi, Gabriele Savarese, Michele Guidotti, Costantino Leonardo, Fabio Ferro, Claudio Manna, Giorgio Franco

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
  6. Article
  7. Review
  8. Article
  9. Pathological and vascular changes in the rat testiсle after experimental trauma.Clinical and experimental reproductive medicine · 2025
    Article
  10. Article
  11. Prevention of New-Onset Heart Failure in Atrial Fibrillation: The Role of Pharmacological Management.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025
    Review
  12. Review
  13. Review
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Antonio FrancoDepartment of Urology, Sant'Andrea Hospital, "Sapienza" University of Rome, 00185 Rome, Italy.
Flavia ProiettiDepartment of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, "Sapienza" University of Rome, 00185 Rome, Italy.ORCID 0000-0002-6478-8584
Veronica PalombiDepartment of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, "Sapienza" University of Rome, 00185 Rome, Italy.
Gabriele SavareseDepartment of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, "Sapienza" University of Rome, 00185 Rome, Italy.
Michele GuidottiDepartment of Urology, Nuovo Ospedale dei Castelli, 00040 Rome, Italy.ORCID 0009-0005-5817-4040
Costantino LeonardoDepartment of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, "Sapienza" University of Rome, 00185 Rome, Italy.
Fabio FerroMater Dei Hospital, 00197 Rome, Italy.
Claudio MannaBiofertility IVF and Infertility Center, 00198 Rome, Italy.ORCID 0000-0001-9145-1955
Giorgio FrancoDepartment of Maternal and Child Health and Urological Sciences, Policlinico Umberto I, "Sapienza" University of Rome, 00185 Rome, Italy.
Policlinico Umberto I · ITAzienda Ospedaliera Sant'Andrea · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Varicocele treatment in infertility still remains controversial. It is clear, in fact, that in many patients, varicocele has no impact on fertility. Recent scientific evidence demonstrated that varicocele treatment is beneficial in improving semen parameters and pregnancy rate when an appropriate selection of patients is made. The purpose of treating varicocele in adults is mainly to improve current fertility status. On the other hand, the goal of treatment in adolescents is to prevent testicular injury and maintain testicular function for future fertility. Hence, the key to the success of varicocele treatment seems to be a correct indication. The aim of this study is to review and summarize current evidence in managing varicocele treatment focusing on the controversies regarding surgical indications in adolescent and adult patients, and in other specific situations such as azoospermia, bilateral or subclinical varicocele, and prior to ART.

Indexed as

ARTinfertilityvaricocelectomyvaricocele repair

Identifiers

PMID37373755
PMCPMC10299325
OpenAlexW4380990885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.