Evidence map›Paper›PMID 37373748›Full record

ArticleJournal of clinical medicine2023

Obesity as a Risk Factor of Severe Outcome of COVID-19: A Pair-Matched 1:2 Case-Control Study.

Antonio Russo, Mariantonietta Pisaturo, Verdiana Zollo, Salvatore Martini, Paolo Maggi, Fabio Giuliano Numis, Ivan Gentile, Nadia Sangiovanni, Anna Maria Rossomando, Vincenzo Bianco and 13 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  4. Article
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  6. Observational
  7. Review
  8. Article
  9. Prediction models for COVID-19 disease outcomes.Emerging microbes & infections · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. The Functions of SARS-CoV-2 Receptors in Diabetes-Related Severe COVID-19.International journal of molecular sciences · 2024
    Review
  15. Article
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 8 institutions in 1 country.

Antonio RussoInfectious Diseases Unit, Department of Mental Health and Public Medicine, University of Campania "L. Vanvitelli", 80138 Napoli, Italy.
Mariantonietta PisaturoInfectious Diseases Unit, Department of Mental Health and Public Medicine, University of Campania "L. Vanvitelli", 80138 Napoli, Italy.
Verdiana ZolloInfectious Diseases Unit, Department of Mental Health and Public Medicine, University of Campania "L. Vanvitelli", 80138 Napoli, Italy.
Salvatore MartiniInfectious Diseases Unit, Department of Mental Health and Public Medicine, University of Campania "L. Vanvitelli", 80138 Napoli, Italy.ORCID 0000-0002-1551-1271
Paolo MaggiInfectious Diseases Unit, A.O. S Anna e S Sebastiano Caserta, 81100 Caserta, Italy.ORCID 0000-0002-8772-0136
Fabio Giuliano NumisEmergency Unit, P.O. Santa Maria delle Grazie, 80078 Pozzuoli, Italy.
Ivan GentileInfectious Disease Unit, Department of Clinical Medicine and Surgery, University Federico II, 80131 Naples, Italy.ORCID 0000-0002-5199-8451
Nadia SangiovanniUOC Systemic and Immunosuppressed Infections, Azienda Ospedaliera di Rilievo Nazionale dei Colli, P.O. Cotugno, 80131 Naples, Italy.
Anna Maria RossomandoIV Infectious Diseases Unit and Gender Medicine, Azienda Ospedaliera di Rilievo Nazionale dei Coli, P.O. Cotugno, 80131 Naples, Italy.
Vincenzo BiancoHepatic Infectious Diseases Unit, Azienda Ospedaliera di Rilievo Nazionale dei Colli, P.O. Cotugno, 80131 Naples, Italy.
Giosuele CalabriaIX Infectious Diseases Unit, Azienda Ospedaliera di Rilievo Nazionale dei Colli, P.O. Cotugno, 80131 Naples, Italy.
Raffaella PisapiaFirst Infectious Diseases Unit, Azienda Ospedaliera di Rilievo Nazionale dei Coli, P.O. Cotugno, 80131 Naples, Italy.
Alessio Vinicio CodellaInfectious Diseases Unit, A.O. San Pio, PO Rummo, 82100 Benevento, Italy.ORCID 0000-0003-1657-6613
Alfonso MasulloInfectious Diseases Unit, A.O. San Giovanni di Dio e Ruggi D'Aragona, 84131 Salerno, Italy.
Elio ManzilloVIII Infectious Diseases Unit, Azienda Ospedaliera di Rilievo Nazionale dei Coli, P.O. Cotugno, 80131 Naples, Italy.
Grazia RussoInfectious Diseases Unit, Ospedale Maria S.S. Addolorata di Eboli, 84025 Eboli, Italy.
Roberto ParrellaRespiratory Infectious Diseases Unit, Azienda Ospedaliera di Rilievo Nazionale dei Colli, P.O. Cotugno, 80131 Naples, Italy.
Giuseppina Dell'AquilaInfectious Diseases Unit, A.O., 83100 Avellino, Italy.
Michele GambardellaInfectious Diseases Unit, P.O. S. Luca, 84078 Vallo della Lucania, Italy.
Antonio PonticielloPneumology Unit and Respiratory Pathophysiology, Azienda Ospedaliera di Rilievo Nazionale Sant' Anna and San Sebastiano, 81100 Caserta, Italy.ORCID 0000-0002-7670-1167
Lorenzo OnoratoInfectious Diseases Unit, Department of Mental Health and Public Medicine, University of Campania "L. Vanvitelli", 80138 Napoli, Italy.
Nicola CoppolaInfectious Diseases Unit, Department of Mental Health and Public Medicine, University of Campania "L. Vanvitelli", 80138 Napoli, Italy.ORCID 0000-0001-5897-4949
CoviCam Group
Ospedale D. Cotugno · ITUniversity of Campania "Luigi Vanvitelli" · ITAzienda Ospedaliera G.Rummo · ITFederico II University Hospital · ITI.R.C.C.S. Oasi Maria SS · ITOspedale Santa Maria · ITOspedale Sant'Anna · ITOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · IT

Funding

Regione Campania POR 2019
6 · The paper itself

Abstract

BACKGROUND AND

aimThe nature of the association between obesity and poor prognosis of COVID-19 without the evaluation of other co-pathologies associated has not yet been clearly evaluated. The aim of the present pair-matched case-control study was to investigate the outcome of patients with SARS-CoV-2 infection in obese and non-obese patients matched considering gender, age, number of comorbidities, and Charlson Comorbidity Index.

methodsAll the adults hospitalized for SARS-CoV-2 infection and with BMI ≥ 30 kg/m

resultsOf the 1282 patients with SARS-CoV-2 infection followed during the study period, 141 patients with obesity and 282 patients without were enrolled in the case and control groups, respectively. Considering matching variables, there was no statistical difference between the two groups. Patients in the Control group developed more frequently a mild-moderate disease (67% vs. 46.1%, respectively), whereas obese patients were more prone to need intensive care treatment (41.8% vs. 26.6%, respectively; DISCUSSION: We confirmed an association between obesity and severe outcome of patients with COVID-19, also considering other factors associated with a severe outcome of COVID-19. Thus, in the case of SARS-CoV-2 infection, the subjects with BMI ≥ 30 kg/m

Indexed as

COVID-19mortalityobesitySARS-CoV-2 infectionseverity of disease

Identifiers

PMID37373748
PMCPMC10298877
OpenAlexW4380997969

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.