Evidence map›Paper›PMID 37373673›Full record

ReviewJournal of clinical medicine2023

Venous Thromboembolism (VTE) in Post-Prostatectomy Patients: Systematic Review and Meta-Analysis.

Mudassir Wani, Abdullah Al-Mitwalli, Subhabrata Mukherjee, Ghulam Nabi, Bhaskar K Somani, Jayasimha Abbaraju, Sanjeev Madaan

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Thromboembolic Events after Surgery for Localized Prostate Cancer: Incidence, Risk Factors, and Survival Outcomes.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Mudassir WaniDepartment of Urology, Swansea Bay University Health Board, Swansea SA6 6NL, UK.ORCID 0000-0001-8940-2310
Abdullah Al-MitwalliDepartment of Urology, Swansea Bay University Health Board, Swansea SA6 6NL, UK.
Subhabrata MukherjeeDepartment of Urology, Imperial College Healthcare NHS Trust, London W6 8RF, UK.
Ghulam NabiSchool of Medicine, Centre for Medical Engineering and Technology, University of Dundee, Dundee DD1 9SY, UK.
Bhaskar K SomaniUrological Surgery Department, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK.ORCID 0000-0002-6248-6478
Jayasimha AbbarajuDepartment of Urology & Nephrology, Dartford, and Gravesham NHS Trust, Dartford DA2 8DA, UK.
Sanjeev MadaanDepartment of Urology & Nephrology, Dartford, and Gravesham NHS Trust, Dartford DA2 8DA, UK.ORCID 0000-0003-4220-5613
Dartford And Gravesham NHS Trust · GBSwansea Bay University Health Board · GBImperial College Healthcare NHS Trust · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Dundee · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radical prostatectomy (RP) is one of the recommended treatments to achieve oncological outcomes in localized prostate cancer. However, a radical prostatectomy is a major abdominopelvic surgery. Venous thromboembolism (VTE) is a well-known complication associated with surgical procedures, including RP. There is a lack of consensus regarding VTE prophylaxis in urological procedures. The aim of this systematic review and meta-analysis was to investigate different aspects of VTE in post-radical prostatectomy patients. A comprehensive literature search was performed, and relevant data were extracted. The primary aim was to perform a systematic review and meta-analysis (wherever possible) of VTE occurrence in post-RP patients in relation to surgical approach, pelvic lymph node dissection, and type of prophylaxis (mechanical or combined prophylaxis). The secondary aim was to investigate the incidence and other risk factors of VTE in post-RP patients. A total of 16 studies were included for quantitative analysis. Statistical methods for analysis included the DerSimonian-Laird random effects. We were able to conclude that the overall incidence of VTE in post-radical prostatectomy is 1% (95% CI) and minimally invasive procedures (MIS), including laparoscopic, as well as robotic procedures for radical prostatectomy and RP without pelvic lymph node dissection (PLND), are associated with less risk of developing VTE. Additional pharmacological prophylaxis to mechanical methods may not be necessary in all cases and should be considered in high-risk patients only.

Indexed as

mechanical prophylaxispharmacological prophylaxisprostate cancerradical prostatectomyvenous thromboembolism

Identifiers

PMID37373673
PMCPMC10299626
OpenAlexW4380363364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.