Evidence map›Paper›PMID 37373611›Full record

ArticleJournal of clinical medicine2023

A Neuropsychiatric Assessment of Children with Previous SARS-CoV-2 Infection.

Veronica Scarselli, Dario Calderoni, Arianna Terrinoni, Chiara Davico, Giulia Pruccoli, Marco Denina, Chiara Carducci, Andrea Smarrazzo, Melania Martucci, Mariaelena Presicce and 7 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Veronica ScarselliDepartment of Human Neuroscience, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-5473-0656
Dario CalderoniDepartment of Human Neuroscience, Sapienza University of Rome, 00185 Rome, Italy.
Arianna TerrinoniDepartment of Human Neuroscience, Sapienza University of Rome, 00185 Rome, Italy.
Chiara DavicoDepartment of Public Health and Pediatric Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0003-4378-8419
Giulia PruccoliDepartment of Public Health and Pediatric Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0003-2250-6048
Marco DeninaDepartment of Public Health and Pediatric Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-8495-1844
Chiara CarducciEmergency, Acceptance and General Pediatrics, Bambino Gesù Children's Hospital, 00165 Rome, Italy.
Andrea SmarrazzoEmergency, Acceptance and General Pediatrics, Bambino Gesù Children's Hospital, 00165 Rome, Italy.ORCID 0000-0001-8947-4429
Melania MartucciDepartment of Human Neuroscience, Sapienza University of Rome, 00185 Rome, Italy.
Mariaelena PresicceDepartment of Human Neuroscience, Sapienza University of Rome, 00185 Rome, Italy.
Daniele MarcotulliDepartment of Public Health and Pediatric Sciences, University of Turin, 10126 Turin, Italy.
Luca ArlettiDepartment of Public Health and Pediatric Sciences, University of Turin, 10126 Turin, Italy.
Mauro FerraraDepartment of Human Neuroscience, Sapienza University of Rome, 00185 Rome, Italy.
Silvia GarazzinoDepartment of Public Health and Pediatric Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-5773-5356
Rosanna MarianiEmergency, Acceptance and General Pediatrics, Bambino Gesù Children's Hospital, 00165 Rome, Italy.
Andrea CampanaEmergency, Acceptance and General Pediatrics, Bambino Gesù Children's Hospital, 00165 Rome, Italy.
Benedetto VitielloDepartment of Public Health and Pediatric Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-8093-7383
University of Turin · ITSapienza University of Rome · ITBambino Gesù Children's Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimConcerns have been raised about possible neuropsychiatric sequelae of COVID-19. The objective of this study was to examine the plausibility of long-term mental health consequences of COVID-19 by assessing a sample of children after the resolution of the acute SARS-CoV-2 infection.

methodAs part of a systematic follow-up assessment of pediatric patients with COVID-19 conducted at two university children's hospitals, 50 children (56% males) aged 8 to 17 years (median 11.5), 26% with previous multisystem inflammatory syndrome in children (MIS-C), without a prior history of neuropsychiatric disorders, received a battery of clinical neuropsychiatric and neuropsychological rating scales that included the Pediatric Migraine Disability Assessment (PedMIDAS), Sleep Disturbance Scale for Children (SDSC), Multidimensional Anxiety Scale for Children (MASC-2), Child Depression Inventory (CDI-2), Child Behavior Checklist (CBCL), and the NEPSY II (Neuropsychological Assessment, Second Edition). The assessments were conducted between 1 and 18 months (median 8 months) after the acute infection.

resultsThe CBCL internalizing symptoms score was in the clinical range for 40% of the participants (vs. a population expected rate of about 10%,

conclusionsThese data from direct assessment of a sample of children who had SARS-CoV-2 infection show higher than expected rates of neuropsychiatric symptoms, thus supporting the possibility that COVID-19 may have mental health sequelae long after the resolution of the acute infection.

Indexed as

adolescentschildrenCOVID-19long-COVIDSARS-CoV-2

Identifiers

PMID37373611
PMCPMC10298991
OpenAlexW4380046223

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.