Evidence map›Paper›PMID 37373608›Full record

ArticleJournal of clinical medicine2023

PEEP Titration Is Markedly Affected by Trunk Inclination in Mechanically Ventilated Patients with COVID-19 ARDS: A Physiologic, Cross-Over Study.

Francesco Marrazzo, Stefano Spina, Francesco Zadek, Clarissa Forlini, Gabriele Bassi, Riccardo Giudici, Giacomo Bellani, Roberto Fumagalli, Thomas Langer

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesco MarrazzoDepartment of Anesthesia and Critical Care, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.ORCID 0000-0001-5407-6615
Stefano SpinaDepartment of Anesthesia and Critical Care, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.ORCID 0000-0003-3210-1714
Francesco ZadekSchool of Medicine and Surgery, University of Milano-Bicocca, 20126 Milano, Italy.ORCID 0000-0002-2377-3992
Clarissa ForliniDepartment of Anesthesia and Critical Care, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.ORCID 0000-0002-1858-1080
Gabriele BassiDepartment of Anesthesia and Critical Care, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.
Riccardo GiudiciDepartment of Anesthesia and Critical Care, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.ORCID 0000-0002-2202-6194
Giacomo BellaniSchool of Medicine and Surgery, University of Milano-Bicocca, 20126 Milano, Italy.ORCID 0000-0002-3089-205X
Roberto FumagalliDepartment of Anesthesia and Critical Care, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.ORCID 0000-0003-0398-1329
Thomas LangerDepartment of Anesthesia and Critical Care, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.ORCID 0000-0002-9725-8520

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChanging trunk inclination affects lung function in patients with ARDS. However, its impacts on PEEP titration remain unknown. The primary aim of this study was to assess, in mechanically ventilated patients with COVID-19 ARDS, the effects of trunk inclination on PEEP titration. The secondary aim was to compare respiratory mechanics and gas exchange in the semi-recumbent (40° head-of-the-bed) and supine-flat (0°) positions following PEEP titration.

methodsTwelve patients were positioned both at 40° and 0° trunk inclination (randomized order). The PEEP associated with the best compromise between overdistension and collapse guided by Electrical Impedance Tomography (PEEP

resultsPEEP

conclusionsA semi-recumbent position is associated with lower PEEP

Indexed as

acute respiratory distress syndromeCOVID-19mechanical ventilationtrunk inclinationventilator-induced lung injury

Identifiers

PMID37373608
PMCPMC10299565

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.