Evidence map›Paper›PMID 37373585›Full record

ArticleJournal of clinical medicine2023

Platelets Rich Plasma (PRP) Procedure in the Healing of Atonic Wounds.

Maur Sebastian Horgos, Ovidiu Laurean Pop, Mircea Sandor, Ioan Lucian Borza, Rodica Anamaria Negrean, Adrian Cote, Andreea-Adriana Neamtu, Carmen Grierosu, Liliana Sachelarie, Anca Huniadi

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Efficacy of Platelet-Rich Plasma and Polyvinyl Alcohol Wound Dressing in Open Wound Healing: First Results from an Experimental Rat Model.European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Maur Sebastian HorgosDepartment of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square No. 10, 410073 Oradea, Romania.ORCID 0000-0001-8828-7517
Ovidiu Laurean PopDepartment of Pathology, County Clinical Emergency Hospital, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square No. 10, 410087 Oradea, Romania.ORCID 0000-0001-7474-4561
Mircea SandorDepartment of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square No. 10, 410073 Oradea, Romania.ORCID 0000-0001-8967-0059
Ioan Lucian BorzaDepartment of Morphological Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square No. 10, 410073 Oradea, Romania.
Rodica Anamaria NegreanDepartment of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square No. 10, 410073 Oradea, Romania.
Adrian CoteDepartment of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square No. 10, 410073 Oradea, Romania.
Andreea-Adriana NeamtuDepartment of Surgical Disciplines, Developmental Biology Biochemistry & Molecular Biology Area Studies Chemistry Communication, Faculty of Medicine and Pharmacy & Dental Medicine, Vasile Goldis Western University, 310045 Arad, Romania.ORCID 0000-0002-5219-5466
Carmen GrierosuDepartment of Preclinical Disciplines, Faculty of Medicine, Apollonia University, Păcurari Street 11, 700511 Iași, Romania.
Liliana SachelarieDepartment of Preclinical Disciplines, Faculty of Medicine, Apollonia University, Păcurari Street 11, 700511 Iași, Romania.ORCID 0000-0001-7701-2307
Anca HuniadiDepartment of Surgical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square No. 10, 410073 Oradea, Romania.ORCID 0000-0002-5998-9488
University of Oradea · ROApollonia University · ROVasile Goldis Western University of Arad · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Patients suffering from chronic wounds report physical, mental, and social consequences due to their existence and care. There is a global need for tissue repair strategies and, in our case, for chronic wound healing. PRP therapy is based on the fact that platelet-derived growth factors (PGF) support the three phases of the wound healing and repair cascade (inflammation, proliferation, and remodeling); (2) Methods: A comparative study was carried out on two groups of patients with atonic wounds totaling a total of 80 cases as follows: a study group in which the PRP procedure was applied and a control group in which the biological product was not injected. The study was carried out in the surgery clinic of the Clinical Hospital C.F. Oradea City; (3) Results: A much faster healing was achieved in the case of patients who benefited from the platelet-rich plasma injection therapy compared to the group of patients in whom this therapy was not used. Three weeks after the plasma injection, a considerable reduction of the wound was evident, with some of the patients presenting with a closed wound; (4) Conclusions: The effect of PRP on the healing of chronic wounds is promising in most cases. A positive effect was also highlighted in terms of reducing treatment costs by considerably reducing the materials used as well as the number of hospitalizations for the same pathology.

Indexed as

atonic woundevolutionhealingnew therapiesplatelet rich plasma

Identifiers

PMID37373585
PMCPMC10299375
OpenAlexW4379793445

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.