Evidence map›Paper›PMID 37373567›Full record

ArticleJournal of clinical medicine2023

Influence of Sociodemographic, Premorbid, and Injury-Related Factors on Post-Traumatic Stress, Anxiety, and Depression after Traumatic Brain Injury.

Fabian Bockhop, Katrin Cunitz, Marina Zeldovich, Anna Buchheim, Tim Beissbarth, York Hagmayer, Nicole von Steinbuechel, CENTER-TBI Participants and Investigators

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Assessment and Management of Post-traumatic Headache.Current neurology and neuroscience reports · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Fabian BockhopInstitute of Medical Psychology and Medical Sociology, University Medical Center Göttingen, 37073 Göttingen, Germany.ORCID 0000-0001-8892-896X
Katrin CunitzInstitute of Medical Psychology and Medical Sociology, University Medical Center Göttingen, 37073 Göttingen, Germany.ORCID 0000-0001-5530-8190
Marina ZeldovichInstitute of Medical Psychology and Medical Sociology, University Medical Center Göttingen, 37073 Göttingen, Germany.ORCID 0000-0003-0172-9904
Anna BuchheimInstitute of Psychology, Faculty of Psychology and Sport Science, University of Innsbruck, 6020 Innsbruck, Austria.ORCID 0000-0002-1339-5246
Tim BeissbarthDepartment of Medical Bioinformatics, University Medical Center Göttingen, 37073 Göttingen, Germany.ORCID 0000-0001-6509-2143
York HagmayerGeorg-Elias-Müller Institute for Psychology, Georg-August-University, 37073 Göttingen, Germany.
Nicole von SteinbuechelInstitute of Medical Psychology and Medical Sociology, University Medical Center Göttingen, 37073 Göttingen, Germany.
CENTER-TBI Participants and Investigators
Universitätsmedizin Göttingen · DEUniversität Innsbruck · ATUniversity of Göttingen · DE

Funding

European Union 7th Framework programme 602150Integra LifeSciences (United States)OneMind (USA)ZNS Hannelore Kohl Stiftung
6 · The paper itself

Abstract

Psychopathological symptoms are common sequelae after traumatic brain injury (TBI), leading to increased personal and societal burden. Previous studies on factors influencing Post-traumatic Stress Disorder (PTSD), Generalized Anxiety Disorder (GAD), and Major Depressive Disorder (MDD) after TBI have produced inconclusive results, partly due to methodological limitations. The current study investigated the influence of commonly proposed factors on the clinical impairment, occurrence, frequency, and intensity of symptoms of PTSD, GAD, and MDD after TBI. The study sample comprised 2069 individuals (65% males). Associations between psychopathological outcomes and sociodemographic, premorbid, and injury-related factors were analyzed using logistic regression, standard, and zero-inflated negative binomial models. Overall, individuals experienced moderate levels of PTSD, GAD, and MDD. Outcomes correlated with early psychiatric assessments across domains. The clinical impairment, occurrence, frequency, and intensity of all outcomes were associated with the educational level, premorbid psychiatric history, injury cause, and functional recovery. Distinct associations were found for injury severity, LOC, and clinical care pathways with PTSD; age and LOC:sex with GAD; and living situation with MDD, respectively. The use of suitable statistical models supported the identification of factors associated with the multifactorial etiology of psychopathology after TBI. Future research may apply these models to reduce personal and societal burden.

Indexed as

generalized anxiety disordermajor depressive disordernegative and zero-inflated negative binomial modelpost-traumatic stress disordertraumatic brain injury

Identifiers

PMID37373567
PMCPMC10299140
OpenAlexW4379799651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.