Evidence map›Paper›PMID 37373465›Full record

ArticleInternational journal of molecular sciences2023

Novel Insights to Assess Climate Resilience in Goats Using a Holistic Approach of Skin-Based Advanced NGS Technologies.

Silpa Mullakkalparambil Velayudhan, Veerasamy Sejian, Chinnasamy Devaraj, Gundallahalli Bayyappa Manjunathareddy, Wilfred Ruban, Vinod Kadam, Sven König, Raghavendra Bhatta

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Genomic advancements in goat breeding: enhancing productivity, disease resistance, and sustainability in India's rural economy.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Silpa Mullakkalparambil VelayudhanInstitute of Animal Breeding and Genetics, Justus Liebig University Giessen, Ludwigstr. 21b, 35390 Giessen, Germany.ORCID 0000-0001-8078-4789
Veerasamy SejianRajiv Gandhi Institute of Veterinary Education and Research, Kurumbapet, Pondicherry 605008, India.ORCID 0000-0002-8224-4521
Chinnasamy DevarajCentre for Climate Resilient Animal Adaptation Studies, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bangalore 560030, India.ORCID 0000-0003-0573-7354
Gundallahalli Bayyappa ManjunathareddyICAR-National Institute of Veterinary Epidemiology and Disease Informatics, Bangalore 560064, India.ORCID 0000-0001-8578-7823
Wilfred RubanDepartment of Livestock Product Technology, Hebbal Veterinary College, Karnataka Veterinary Animal and Fishery Sciences University, Hebbal, Bangalore 560024, India.ORCID 0000-0001-7430-6094
Vinod KadamTextile Manufacturing and Textile Chemistry Division, Central Sheep and Wool Research Institute, Avikanagar, Malpura 304501, India.ORCID 0000-0001-6206-9271
Sven KönigInstitute of Animal Breeding and Genetics, Justus Liebig University Giessen, Ludwigstr. 21b, 35390 Giessen, Germany.ORCID 0000-0003-4226-3696
Raghavendra BhattaCentre for Climate Resilient Animal Adaptation Studies, ICAR-National Institute of Animal Nutrition and Physiology, Adugodi, Bangalore 560030, India.
National Institute of Animal Nutrition and Physiology · INJustus-Liebig-Universität Gießen · DECentral Sheep and Wool Research Institute · INKarnataka Veterinary Animal and Fisheries Sciences University · INNational Institute Of Veterinary Epidemiology And Disease Informatics · IN

Funding

Indian Council of Agricultural Research 2020
6 · The paper itself

Abstract

A novel study was conducted to elucidate heat-stress responses on a number of hair- and skin-based traits in two indigenous goat breeds using a holistic approach that considered a number of phenotypic and genomic variables. The two goat breeds, Kanni Aadu and Kodi Aadu, were subjected to a simulated heat-stress study using the climate chambers. Four groups consisting of six goats each (KAC, Kaani Aadu control; KAH, Kanni Aadu heat stress; KOC, Kodi Aadu control; and KOH, Kodi Aadu heat stress) were considered for the study. The impact of heat stress on caprine skin tissue along with a comparative assessment of the thermal resilience of the two goat breeds was assessed. The variables considered were hair characteristics, hair cortisol, hair follicle quantitative PCR (qPCR), sweating (sweating rate and active sweat gland measurement), skin histometry, skin-surface infrared thermography (IRT), skin 16S rRNA V3-V4 metagenomics, skin transcriptomics, and skin bisulfite sequencing. Heat stress significantly influenced the hair fiber characteristics (fiber length) and hair follicle qPCR profile (

Indexed as

GoatsHeat Stress DisordersAnimalsHairHSP70 Heat-Shock ProteinsRNA, Ribosomal, 16SSkinHSP70 Heat-Shock ProteinsRNA, Ribosomal, 16SDNA methylationgoatsheat stressmetagenomicsskintranscriptomics

Identifiers

PMID37373465
PMCPMC10298993
OpenAlexW4381166381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.