Evidence map›Paper›PMID 37373415›Full record

ArticleInternational journal of molecular sciences2023

Prediction of Antifungal Activity of Antimicrobial Peptides by Transfer Learning from Protein Pretrained Models.

Fernando Lobo, Maily Selena González, Alicia Boto, José Manuel Pérez de la Lastra

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fernando LoboPrograma Agustín de Betancourt, Universidad de La Laguna, 38206 La Laguna, Tenerife, Spain.
Maily Selena GonzálezInstituto de Productos Naturales y Agrobiología del CSIC, Avda. Astrofísico Fco. Sánchez, 3, 38206 La Laguna, Tenerife, Spain.
Alicia BotoInstituto de Productos Naturales y Agrobiología del CSIC, Avda. Astrofísico Fco. Sánchez, 3, 38206 La Laguna, Tenerife, Spain.ORCID 0000-0002-7120-679X
José Manuel Pérez de la LastraInstituto de Productos Naturales y Agrobiología del CSIC, Avda. Astrofísico Fco. Sánchez, 3, 38206 La Laguna, Tenerife, Spain.ORCID 0000-0003-4663-5565

Funding

Cabildo de Tenerife (with MEDI & FDCAN Funds) Agustín de Betancourt (to FL)CajaCanarias Project 2019SP43Conexión de Nanomedicina of the Spanish Research Council (CSIC) JAE Intro-ICU (Reference: JAEICU-21-IQM-20, Red Conexión Instituto de Química Médica)European FEDER Funds PID2020-116688RB-C21Information Resources for Research Unit (URICI)-CSIC CSIC Open Access Publication Support InitiativeMinisterio de Ciencia e Innovación PID2020-116688RB-C21
6 · The paper itself

Abstract

Peptides with antifungal activity have gained significant attention due to their potential therapeutic applications. In this study, we explore the use of pretrained protein models as feature extractors to develop predictive models for antifungal peptide activity. Various machine learning classifiers were trained and evaluated. Our AFP predictor achieved comparable performance to current state-of-the-art methods. Overall, our study demonstrates the effectiveness of pretrained models for peptide analysis and provides a valuable tool for predicting antifungal peptide activity and potentially other peptide properties.

Indexed as

Antifungal AgentsAntimicrobial PeptidesMachine LearningPeptidesAntifungal AgentsAntimicrobial PeptidesPeptidesantifungal peptidesantimicrobial peptidesmachine learningtransfer learning

Identifiers

PMID37373415
PMCPMC10299371

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.