Evidence map›Paper›PMID 37373325›Full record

ArticleInternational journal of molecular sciences2023

Less Severe Polymicrobial Sepsis in Conditional

Kritsanawan Sae-Khow, Pornpimol Phuengmaung, Jiraphorn Issara-Amphorn, Jiradej Makjaroen, Peerapat Visitchanakun, Atsadang Boonmee, Salisa Benjaskulluecha, Tanapat Palaga, Asada Leelahavanichkul

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. The Coexistence ofInternational journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kritsanawan Sae-KhowMedical Microbiology, Interdisciplinary and International Program, Graduate School, Chulalongkorn University, Bangkok 10330, Thailand.
Pornpimol PhuengmaungDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Jiraphorn Issara-AmphornCenter of Excellence in Translational Research in Inflammation and Immunology (CETRII), Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Jiradej MakjaroenCenter of Excellence in Systems Biology, Research Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0001-6025-0106
Peerapat VisitchanakunDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Atsadang BoonmeeDepartment of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Salisa BenjaskulluechaDepartment of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Tanapat PalagaDepartment of Microbiology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Asada LeelahavanichkulMedical Microbiology, Interdisciplinary and International Program, Graduate School, Chulalongkorn University, Bangkok 10330, Thailand.
Chulalongkorn University · TH

Funding

Intramural Research Program of National Institute of Allergy and Infectious Diseases (NIAID), National Insti-tutes of Health (NIH) (NIAID)National Research Council of Thailand 811/2563National Research Council of Thailand NRCT-N34A660583National Research Council of Thailand NRCT-N41A640076NSRF via the Program Management Unit for Human Resources & Institutional Development, Research and In-novation B16F640175NSRF via the Program Management Unit for Human Resources & Institutional Development, Research and In-novation B36G660003Rachadapisek Sompote Matching Fund RA-MF-13/66Rachadapisek Sompote Matching Fund RA-MF-22/65Second Century Fund (C2F) for high-efficiency Ph.D. candidates, Chulalongkorn University (C2F)Thailand Science research and Innovation Fund, Chulalongkorn University HEA663000017
6 · The paper itself

Abstract

The O6-methylguanine-DNA methyltransferase (MGMT) is a DNA suicide repair enzyme that might be important during sepsis but has never been explored. Then, the proteomic analysis of lipopolysaccharide (LPS)-stimulated wild-type (WT) macrophages increased proteasome proteins and reduced oxidative phosphorylation proteins compared with control, possibly related to cell injury. With LPS stimulation,

Indexed as

LipopolysaccharidesSepsisAnimalsCytokinesDNADNA MethylationIntegrasesMiceMice, Inbred C57BLMice, KnockoutProteomicsTumor Necrosis Factor-alphaCre recombinaseCytokinesDNAIntegrasesLipopolysaccharidesTumor Necrosis Factor-alphaepigeneticslipopolysaccharidemacrophagesmgmtsepsis

Identifiers

PMID37373325
PMCPMC10299382
OpenAlexW4380992891

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.