Evidence map›Paper›PMID 37373226›Full record

ArticleInternational journal of molecular sciences2023

Optimization of Mass Spectrometry Imaging for Drug Metabolism and Distribution Studies in the Zebrafish Larvae Model: A Case Study with the Opioid Antagonist Naloxone.

Yu Mi Park, Markus R Meyer, Rolf Müller, Jennifer Herrmann

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Yu Mi ParkHelmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus E8 1, Saarland University, 66123 Saarbrücken, Germany.
Markus R MeyerCenter for Molecular Signaling (PZMS), Institute of Experimental and Clinical Pharmacology and Toxicology, Department of Experimental and Clinical Toxicology, Saarland University, 66421 Homburg, Germany.ORCID 0000-0003-4377-6784
Rolf MüllerHelmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus E8 1, Saarland University, 66123 Saarbrücken, Germany.ORCID 0000-0002-1042-5665
Jennifer HerrmannHelmholtz Centre for Infection Research, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Campus E8 1, Saarland University, 66123 Saarbrücken, Germany.ORCID 0000-0003-3398-9938
German Center for Infection Research · DEKIST Europe · DESaarland University · DE

Funding

KIST Europe Signature Research 22101Korea government (MSIP) National Research Council of Science and Technology (NST) grant CAP-17-01-KIST Europe
6 · The paper itself

Abstract

Zebrafish (ZF;

Indexed as

Narcotic AntagonistsZebrafishAnimalsHumansLarvaMass SpectrometryNaloxonePilot ProjectsNaloxoneNarcotic Antagonistsdrug metabolism and pharmacokinetics (DMPK)mass spectrometry imaging (MSI)naloxoneopioid antagonistspatial drug distributionzebrafish larvae model

Identifiers

PMID37373226
PMCPMC10298338
OpenAlexW4380684314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.