Evidence map›Paper›PMID 37373212›Full record

ArticleInternational journal of molecular sciences2023

Plasma Galectin-4 Levels Are Increased after Stroke in Mice and Humans.

Amra Jujic, João P P Vieira, Hana Matuskova, Peter M Nilsson, Ulf Lindblad, Michael H Olsen, João M N Duarte, Anja Meissner, Martin Magnusson

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Amra JujicWallenberg Centre for Molecular Medicine, Lund University, 22100 Lund, Sweden.ORCID 0000-0002-9506-0158
João P P VieiraWallenberg Centre for Molecular Medicine, Lund University, 22100 Lund, Sweden.
Hana MatuskovaWallenberg Centre for Molecular Medicine, Lund University, 22100 Lund, Sweden.
Peter M NilssonDepartment of Clinical Sciences, Lund University, 20502 Malmö, Sweden.ORCID 0000-0002-5652-8459
Ulf LindbladGeneral Practice-Family Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 40530 Gothenburg, Sweden.
Michael H OlsenDepartment of Internal Medicine 1, Holbaek Hospital, 4300 Holbaek, Denmark.
João M N DuarteWallenberg Centre for Molecular Medicine, Lund University, 22100 Lund, Sweden.ORCID 0000-0001-5984-1574
Anja MeissnerWallenberg Centre for Molecular Medicine, Lund University, 22100 Lund, Sweden.ORCID 0000-0002-0793-7213
Martin MagnussonWallenberg Centre for Molecular Medicine, Lund University, 22100 Lund, Sweden.ORCID 0000-0003-1710-5936
Lund University · SEUniversity of Augsburg · DEUniversity of Gothenburg · SEUniversity of Southern Denmark · DK

Funding

Crafoord Foundation 20220566Crafoord Foundation 20220654Diabetesfonden Dia2019-440Direktör Albert Påhlssons Foundation AM 2021-23, JMND 2020-23German Academic Exchange Service 2021Heart and Lung Foundation of Sweden 2004045806Heart and Lung Foundation of Sweden 20210354Hjärnfonden FO2021-0112Sparbanken Stiftelse V2021/1851Swedish Research Council 2019-01130Swedish Research Council 2022-00973
6 · The paper itself

Abstract

Epidemiological studies have associated plasma galectin-4 (Gal-4) levels with prevalent and incident diabetes, and with an increased risk of coronary artery disease. To date, data regarding possible associations between plasma Gal-4 and stroke are lacking. Using linear and logistic regression analyses, we tested Gal-4 association with prevalent stroke in a population-based cohort. Additionally, in mice fed a high-fat diet (HFD), we investigated whether plasma Gal-4 increases in response to ischemic stroke. Plasma Gal-4 was higher in subjects with prevalent ischemic stroke, and was associated with prevalent ischemic stroke (odds ratio 1.52; 95% confidence interval 1.01-2.30;

Indexed as

Ischemic StrokeStrokeAnimalsBiomarkersGalectin 3Galectin 4GalectinsHumansMiceBiomarkersGalectin 3Galectin 4Galectinscardiovascular diseasediabetesgalectinsischemic strokeobesity

Identifiers

PMID37373212
PMCPMC10298636
OpenAlexW4380611668

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.