Evidence map›Paper›PMID 37373199›Full record

ArticleInternational journal of molecular sciences2023

Temporal and Spatial Patterns of Inflammation and Tissue Injury in Patients with Postoperative Respiratory Failure after Lung Resection Surgery: A Nested Case-Control Study.

Jay Kormish, Tejas Ghuman, Richard Y Liu, Sadeesh K Srinathan, Lawrence Tan, Kristen Graham, Stephanie Enns, Gordon Buduhan, Andrew J Halayko, Christopher D Pascoe and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jay KormishSection of Thoracic Surgery, Department of Surgery, Health Sciences Centre, Winnipeg, MB R3A 1R9, Canada.ORCID 0000-0003-2974-8533
Tejas GhumanDepartment of Surgery, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3A 1R9, Canada.
Richard Y LiuSection of Thoracic Surgery, Department of Surgery, Health Sciences Centre, Winnipeg, MB R3A 1R9, Canada.
Sadeesh K SrinathanSection of Thoracic Surgery, Department of Surgery, Health Sciences Centre, Winnipeg, MB R3A 1R9, Canada.
Lawrence TanDepartment of Surgery, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB R3A 1R9, Canada.
Kristen GrahamSection of Thoracic Surgery, Department of Surgery, Health Sciences Centre, Winnipeg, MB R3A 1R9, Canada.
Stephanie EnnsSection of Thoracic Surgery, Department of Surgery, Health Sciences Centre, Winnipeg, MB R3A 1R9, Canada.
Gordon BuduhanSection of Thoracic Surgery, Department of Surgery, Health Sciences Centre, Winnipeg, MB R3A 1R9, Canada.
Andrew J HalaykoChildren's Hospital Research Institute of Manitoba, Winnipeg, MB R3A 1R9, Canada.
Christopher D PascoeChildren's Hospital Research Institute of Manitoba, Winnipeg, MB R3A 1R9, Canada.
Biniam KidaneSection of Thoracic Surgery, Department of Surgery, Health Sciences Centre, Winnipeg, MB R3A 1R9, Canada.ORCID 0000-0002-2982-2505
Health Sciences Centre · CAChildren's Hospital Research Institute of Manitoba · CAUniversity of Manitoba · CA

Funding

Dr. Paul H.T. Thorlakson Foundation Fund 57064Research Manitoba 50183University of Manitoba GFT Surgery Research Grant NA
6 · The paper itself

Abstract

Thoracic surgeries involving resection of lung tissue pose a risk of severe postoperative pulmonary complications, including acute respiratory distress syndrome (ARDS) and respiratory failure. Lung resections require one-lung ventilation (OLV) and, thus, are at higher risk of ventilator-induced lung injury (VILI) attributable to barotrauma and volutrauma in the one ventilated lung, as well as hypoxemia and reperfusion injury on the operated lung. Further, we also aimed to assess the differences in localized and systemic markers of tissue injury/inflammation in those who developed respiratory failure after lung surgery versus matched controls who did not develop respiratory failure. We aimed to assess the different inflammatory/injury marker patterns induced in the operated and ventilated lung and how this compared to the systemic circulating inflammatory/injury marker pattern. A case-control study nested within a prospective cohort study was performed. Patients with postoperative respiratory failure after lung surgery (

Indexed as

LungRespiratory InsufficiencyCase-Control StudiesHumansInflammationPostoperative ComplicationsProspective StudiesRespiration, Artificialacute lung injury (ALI)acute respiratory distress syndrome (ARDS)one-lung ventilation (OLV)postoperative pulmonary complications (PPCs)ventilation-induced lung injury (VILI)

Identifiers

PMID37373199
PMCPMC10298093
OpenAlexW4380486460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.