Evidence map›Paper›PMID 37373054›Full record

ArticleInternational journal of molecular sciences2023

Hepatic Global Transcriptomic Profiles of Holstein Cows According to Parity Reveal Age-Related Changes in Early Lactation.

Zhangrui Cheng, Conrad Ferris, Mark A Crowe, Klaus L Ingvartsen, Clément Grelet, Amélie Vanlierde, Leslie Foldager, Frank Becker, D Claire Wathes, The GplusE Consortium

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 5 countries.

Zhangrui ChengDepartment of Pathobiology and Population Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK.ORCID 0000-0002-1559-5735
Conrad FerrisAgri-Food and Biosciences Institute, Newforge Lane, Upper Malone Road, Belfast BT9 5PX, UK.ORCID 0000-0001-8623-5983
Mark A CroweSchool of Veterinary Medicine, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.ORCID 0000-0003-1999-815X
Klaus L IngvartsenDepartment of Animal and Veterinary Sciences, Aarhus University, Blichers Allé 20, 8830 Tjele, Denmark.ORCID 0000-0003-2372-563X
Clément GreletValorisation of Agricultural Products Department, Walloon Agricultural Research Centre, 5030 Gembloux, Belgium.ORCID 0000-0003-3313-485X
Amélie VanlierdeValorisation of Agricultural Products Department, Walloon Agricultural Research Centre, 5030 Gembloux, Belgium.ORCID 0000-0002-4619-1936
Leslie FoldagerDepartment of Animal and Veterinary Sciences, Aarhus University, Blichers Allé 20, 8830 Tjele, Denmark.ORCID 0000-0002-2639-826X
Frank BeckerResearch Institute for Farm Animal Biology, Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany.ORCID 0000-0001-9832-3091
D Claire WathesDepartment of Pathobiology and Population Sciences, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK.ORCID 0000-0002-8206-6091
The GplusE Consortium
Aarhus University · DKRoyal Veterinary College · GBWalloon Agricultural Research Centre · BEAgri Food and Biosciences Institute · GBResearch Institute for Farm Animal Biology (FBN) · DEUniversity College Dublin · IE

Funding

European Union 613689
6 · The paper itself

Abstract

Cows can live for over 20 years, but their productive lifespan averages only around 3 years after first calving. Liver dysfunction can reduce lifespan by increasing the risk of metabolic and infectious disease. This study investigated the changes in hepatic global transcriptomic profiles in early lactation Holstein cows in different lactations. Cows from five herds were grouped as primiparous (lactation number 1, PP, 534.7 ± 6.9 kg,

Indexed as

LactationTranscriptomeAnimalsCattleFemaleLiverMilkParityPregnancyageageingcellular senescencecowsimmunitylactationlivermetabolismtranscriptome

Identifiers

PMID37373054
PMCPMC10298156
OpenAlexW4380081918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.