Evidence map›Paper›PMID 37372972›Full record

ArticleInternational journal of molecular sciences2023

Impact of IDH Mutations, the 1p/19q Co-Deletion and the G-CIMP Status on Alternative Splicing in Diffuse Gliomas.

Lu Zhang, Sabrina Fritah, Petr V Nazarov, Tony Kaoma, Eric Van Dyck

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lu ZhangBioinformatics Platform, Data Integration and Analysis Unit (DIA), Luxembourg Institute of Health (LIH), L-1445 Strassen, Luxembourg.ORCID 0000-0001-7141-6730
Sabrina FritahNorLux Neuro-Oncology Laboratory, Department of Cancer Research (DoCR), Luxembourg Institute of Health (LIH), L-1445 Strassen, Luxembourg.
Petr V NazarovBioinformatics Platform, Data Integration and Analysis Unit (DIA), Luxembourg Institute of Health (LIH), L-1445 Strassen, Luxembourg.ORCID 0000-0003-3443-0298
Tony KaomaBioinformatics Platform, Data Integration and Analysis Unit (DIA), Luxembourg Institute of Health (LIH), L-1445 Strassen, Luxembourg.ORCID 0000-0002-1269-4826
Eric Van DyckDNA Repair and Chemoresistance Group, DoCR, Luxembourg Institute of Health (LIH), L-1445 Strassen, Luxembourg.ORCID 0000-0001-8614-2402
Luxembourg Institute of Health · LU

Funding

Luxembourg National Research Fund (FNR) grant C21/BM/15739125/DIOMEDES
6 · The paper itself

Abstract

By generating protein diversity, alternative splicing provides an important oncogenic pathway. Isocitrate dehydrogenase (

Indexed as

Brain NeoplasmsGliomaAlternative SplicingChromosome AberrationsEpigenesis, GeneticHumansIsocitrate DehydrogenaseMutationPhenotypeIsocitrate Dehydrogenase1p/19q co-deletionalternative splicingdifferential gene expressiondiffuse gliomasepigenetic regulationG-CIMPisocitrate dehydrogenase (IDH)pre-mRNA splicing

Identifiers

PMID37372972
PMCPMC10297931
OpenAlexW4379793427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.