Synthesis of Novel Antimicrobial CHX-CaCl

Hawraa F Alostath, Domniki Chatzopoulou, Simon Holmes, David Gould, Gleb Sukhorukov, Michael J Cattell

Open access · goldAbstract read

In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.3field-weighted citation impact, top 48% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

Special Issue "Drug Discovery and Application of New Technologies".International journal of molecular sciences · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hawraa F AlostathCentre for Oral Bioengineering, Bart's and the London, School of Medicine and Dentistry, Queen Mary University of London, London E1 2AD, UK.ORCID 0000-0003-1210-8361

Domniki ChatzopoulouCentre for Oral Bioengineering, Bart's and the London, School of Medicine and Dentistry, Queen Mary University of London, London E1 2AD, UK.

Simon HolmesBarts Health NHS Trust, Department of Oral and Maxillofacial Surgery, Queen Mary University of London, London E1 1FR, UK.

David GouldCentre for Biochemical Pharmacology, William Harvey Research Institute, Queen Mary University of London, London EC1M 6BQ, UK.

Gleb SukhorukovInstitute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, London E1 4NS, UK.ORCID 0000-0001-6213-0562

Michael J CattellCentre for Oral Bioengineering, Bart's and the London, School of Medicine and Dentistry, Queen Mary University of London, London E1 2AD, UK.ORCID 0000-0002-5561-4531

Queen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maxillofacial surgery placement of fixatures (Leonard Buttons, LB) at close proximity to surgical incisions provides a potential reservoir as a secondary local factor to advanced periodontal disease, with bacterial formation around failed fixatures implicating plaque. To address infection rates, we aimed to surface coat LB and Titanium (Ti) discs using a novel form of chlorhexidine (CHX), CHX-CaCl

Indexed as

Anti-Infective AgentsPeriodontal DiseasesBacteriaCalcium ChlorideChlorhexidineHumansMouthwashesTitaniumAnti-Infective AgentsCalcium ChlorideChlorhexidineMouthwashesTitaniumantimicrobialchlorhexidinecrystallisationdrug deliverydrug synthesismaxillofacial

Identifiers

PMID37372949

DOI10.3390/ijms24129801

PMCPMC10298500

OpenAlexW4379514150

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.