ReviewHealthcare (Basel, Switzerland)2023
MIH and Dental Caries in Children: A Systematic Review and Meta-Analysis.
Review in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- In vitro remineralization effectiveness of eggshell extract on human teeth: a systematic review and meta-analysis.Odontology · 2026Pooled it
- Prevalence of molar-incisor hypomineralisation (MIH) in children in the Gulf Cooperation Council countries: a systematic review and meta-analysis.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Pooled it
- Diagnostic Indices for Epidemiological Assessment of Molar Incisor Hypomineralization: A Systematic Review.Calcified tissue international · 2026Pooled it
- Activity and levels of TNF-α, IL-6 and IL-8 in saliva of children and young adults with dental caries: a systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Article
- Prevalence and severity of molar incisor hypomineralization among children in Madinah, Saudi Arabia: A school-based cross-sectional study.BMC oral health · 2026Article
- The association of caries prevalence and experience in relation with molar incisor hypomineralisation and its associated factors in Mexican schoolchildren: a cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Long-term evaluation of the success rate of different treatment modalities on MIH-affected teeth.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Mapping the ECC-Saliva Neuroimmune Axis Using AI: A System-Level Framework.Children (Basel, Switzerland) · 2026Article
- Clinical management of severe molar-incisor hypomineralisation using CAD/CAM fabricated PMMA crowns: a case report.Biomaterial investigations in dentistry · 2026Article
- Prevalence of dental caries and its association with molar incisor hypomineralization among 7-10-year-old children in Jeddah, Saudi Arabia. An epidemiological study.The Saudi dental journal · 2025Article
- From Microstructure to Shade Shift: Confocal and Spectrophotometric Evaluation of Peroxide-Induced Dental Bleaching.Journal of clinical medicine · 2025Article
- Aetiological factors in molar incisor hypomineralisation: a case-control study from Salamanca, Spain.Italian journal of pediatrics · 2025Observational
- Risk for molar incisor hypomineralization in children with hypomineralizations in the deciduous dentition: a case-control study on children from a Swiss suburban region.BMC oral health · 2025Article
- Review
- Factors affecting pain experience after lower third molar germectomy in teenagers-a clinical study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Article
- Regional Epidemiological Study on the Dental Status of the First Permanent Molar in Romanian Schoolchildren.Dentistry journal · 2025Article
- Prevalence of Hypomineralized Second Primary Molar in Shaanxi, China.Frontiers in public health · 2025Article
- Is there an association between molar-incisor hypomineralization and carious lesions in seven to ten-year-old Brazilian schoolchildren? A cross-sectional study.Journal of applied oral science : revista FOB · 2025Article
- Investigation of the frequency of molar incisor hypomineralisation in childhood celiac disease and evaluation with nutritional factors and calcium metabolism.Frontiers in pediatrics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
(1) Background: Molar-incisor hypomineralization (MIH) is a clinical condition affecting permanent teeth in children, with a documented rising trend in the last two decades. The aim of the present study was to analyze and synthesize the available evidence on caries experience (dmft/DMFT) and MIH in children. (2) Methods: A systematic review and meta-analysis were conducted according to the PRISMA statement. (3) Results: 59 papers published between 2007 and 2022 were included in the qualitative synthesis and 18 in the meta-analysis. The total sample of subjects was 17,717 (mean: 896), of which 2378 (13.4%) had MIH (mean: 119), with a girl/boy ratio of 1:1. The mean age of the enrolled participants was 8.6 (age range 7-10 years). Meta-analysis showed that MIH has a positive correlation with both dmft (effect size of 0.67, 95% CI [0.15, 1.19]) and DMFT (effect size of 0.56, 95% CI [0.41, 0.72]); (4) Conclusions: Children with MIH should be diagnosed correctly and on time. Treatment and management options for moderate and severe forms of MIH should consider prognosis based on known risk factors, and secondary and tertiary prevention policies should also consider the multifactorial nature of caries etiology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.