ArticleFoods (Basel, Switzerland)2023
Gastroprotective Effects of the Aqueous Extract of Finger Citron Pickled Products against Ethanol-Induced Gastric Damage: In Vitro and In Vivo Studies.
Article in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 10 citations in OpenAlex.
- Structural Characterization and In Vivo Gastric Mucosal Protective Activity of a Polysaccharide from Laoxianghuang (Fermented Finger Citron) in Mice.International journal of molecular sciences · 2026Article
- Untargeted Metabolomics Reveals Organ-Specific Metabolites Associated with Antioxidant and Anti-Inflammatory Activities in Finger Citron (Metabolites · 2026Article
- Pretreatment withNutrients · 2025Article
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Authors and funding
4 authors at 1 institution in 1 country.
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Abstract
Finger citron pickled products (FCPP), as folk remedies, are famous in southern China for protecting gastric mucosa. However, the gastric mucosa protection of FCPP has not been reported yet, and its effective mechanism is unclear. In this study, the protective mechanism of FCPP aqueous extract on gastric mucosa was investigated in vitro and in vivo for the first time, using human gastric mucosa epithelial cells (GES-1) and acute alcoholic gastric ulcer rat model respectively. Furthermore, we also investigated the main substances in the aqueous extract that exert gastroprotective activity using a GES-1 scratch test and basic chemical composition analysis. FCPP aqueous extract was found to play a protective and reparative role in GES-1 by promoting the secretion of trefoil factor thyroid transcription factor 2 (TFF2) and inhibiting the secretion of tumor necrosis factor-
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