Evidence map›Paper›PMID 37372387›Full record

ArticleGenes2023

The Mouse CircGHR Regulates Proliferation, Differentiation and Apoptosis of Hepatocytes and Myoblasts.

Weilu Zhang, Shudai Lin, Zhenhai Jiao, Lilong An, Tingting Xie, Jiang Wu, Li Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Weilu ZhangCollege of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.
Shudai LinCollege of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.ORCID 0000-0002-8520-8614
Zhenhai JiaoCollege of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.
Lilong AnCollege of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.
Tingting XieCollege of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.
Jiang WuExperimental Teaching Center, Guangdong Ocean University, Zhanjiang 524088, China.ORCID 0000-0002-0771-1791
Li ZhangCollege of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China.
Guangdong Ocean University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anterior pituitary gland of animals secretes growth hormone (GH) to bind to the growth hormone receptor (GHR) on the liver cell membrane through the blood circulation, thereby promoting the downstream gene insulin-like growth factor-1 (IGF1) expression, which is the canonical GH-GHR-IGF1 signaling pathway. Therefore, the amount of GHR and the integrity of its structure will affect animal growth and development. In the previous study, we found that the mouse

Indexed as

HepatocytesReceptors, SomatotropinAnimalsApoptosisCell DifferentiationCell ProliferationMiceMyoblastsReceptors, SomatotropinC2C12cell proliferationcircGHRmouseNCTC1469

Identifiers

PMID37372387
PMCPMC10298241
OpenAlexW4379055345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.