Evidence map›Paper›PMID 37372364›Full record

ArticleGenes2023

Association between Aldosterone Synthase (

Waheed Ali Shah, Asif Jan, Muhammad Asghar Khan, Muhammad Saeed, Naveed Rahman, Zakiullah, Muhammad Sajjad Afridi, Fazli Khuda, Rani Akbar

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Diuretic effects of Hecogenin and Hecogenin acetate via aldosterone synthase inhibition.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Waheed Ali ShahDepartment of Pharmacy, University of Peshawar, Peshawar 25000, Pakistan.
Asif JanDepartment of Pharmacy, University of Peshawar, Peshawar 25000, Pakistan.ORCID 0000-0003-3880-5579
Muhammad Asghar KhanCardiology Unit Hayatabad Medical Complex, Peshawar 25000, Pakistan.
Muhammad SaeedDepartment of Pharmacy, Qurtaba University of Science and Technology, Peshawar 25000, Pakistan.
Naveed RahmanDepartment of Pharmacy, University of Peshawar, Peshawar 25000, Pakistan.ORCID 0009-0007-0640-4320
ZakiullahDepartment of Pharmacy, University of Peshawar, Peshawar 25000, Pakistan.ORCID 0000-0001-7932-9498
Muhammad Sajjad AfridiDepartment of Pharmacy, Qurtaba University of Science and Technology, Peshawar 25000, Pakistan.
Fazli KhudaDepartment of Pharmacy, University of Peshawar, Peshawar 25000, Pakistan.ORCID 0000-0002-6847-1744
Rani AkbarDepartment of Pharmacy, Abdul Wali Khan University, Mardan 23200, Pakistan.
University of Peshawar · PKQurtuba University of Science and Information Technology · PKAbdul Wali Khan University Mardan · PKHayatabad Medical Complex · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome-wide association studies significantly increased the number of hypertension risk variants; however, most of them focused on European societies. There is lack of such studies in developing countries, including Pakistan. The lack of research studies and the high prevalence of hypertension in the Pakistani community prompted us to design this study. Aldosterone synthase (

Indexed as

Cytochrome P-450 CYP11B2HypertensionAdultAldosteroneEthnicityGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansPakistanPolymorphism, Single NucleotideAldosteroneCytochrome P-450 CYP11B2blood pressure (BP)genotypinghypertension (HTN)PakistanPashtunrisk variantsSingle Nucleotide Polymorphism (SNPs)whole exome sequencing (WES)

Identifiers

PMID37372364
PMCPMC10297898
OpenAlexW4378716981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.