Evidence map›Paper›PMID 37372339›Full record

ArticleGenes2023

Analysis of the Origin of Emiratis as Inferred from a Family Study Based on

Zain Al Yafei, Abdelhafidh Hajjej, Marion Alvares, Ayeda Al Mahri, Amre Nasr, Rajaa Mirghani, Ali Al Obaidli, Mohamed Al Seiari, Steven J Mack, Medhat Askar and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zain Al YafeiSheikh Khalifa Medical City-Union71-Purehealth, Abu Dhabi P.O. Box 51900, United Arab Emirates.
Abdelhafidh HajjejDepartment of Immunogenetics, National Blood Transfusion Center, Tunis P.O. Box 1006, Tunisia.
Marion AlvaresSheikh Khalifa Medical City-Union71-Purehealth, Abu Dhabi P.O. Box 51900, United Arab Emirates.
Ayeda Al MahriSheikh Khalifa Medical City-Union71-Purehealth, Abu Dhabi P.O. Box 51900, United Arab Emirates.
Amre NasrCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh P.O. Box 22490, Saudi Arabia.
Rajaa MirghaniHigher College of Technology, Abu Dhabi P.O. Box 25026, United Arab Emirates.
Ali Al ObaidliSEHA Kidney Care, SEHA, Abu Dhabi P.O. Box 92900, United Arab Emirates.
Mohamed Al SeiariSEHA Kidney Care, SEHA, Abu Dhabi P.O. Box 92900, United Arab Emirates.
Steven J MackDepartment of Pediatrics, University of California, San Francisco, Oakland, CA 94609, USA.
Medhat AskarQatar University, Doha P.O. Box 2713, Qatar.
Hisham A EdinurSchool of Health Sciences, Universiti Sains Malaysia, Health Campus, Kubang Kerian 16150, Kelantan, Malaysia.ORCID 0000-0002-3379-6063
Wassim Y AlmawiFaculty of Sciences, El-Manar University, Tunis P.O. Box 94, Tunisia.ORCID 0000-0003-1633-9757
Gehad ElGhazaliSheikh Khalifa Medical City-Union71-Purehealth, Abu Dhabi P.O. Box 51900, United Arab Emirates.ORCID 0000-0001-9514-3765

Funding

Integrated Exchange and Storage of Current- and Future-Generation Immunogenomic DataR01AI128775 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JILL Allison HOLLENBACH, STEVEN JOHN MACK · 2017 to 2026
$4.5M
NIAID NIH HHS R01 AI128775
6 · The paper itself

Abstract

In this study, we investigated HLA class I and class II allele and haplotype frequencies in Emiratis and compared them to those of Asian, Mediterranean, and Sub-Saharan African populations.

methodsTwo-hundred unrelated Emirati parents of patients selected for bone marrow transplantation were genotyped for HLA class I (

resultsThe studied HLA loci were in Hardy-Weinberg Equilibrium. We identified 17

conclusionsEmiratis were closely related to Arabian Peninsula populations, West Mediterranean populations and Pakistanis. However, the contribution of East Mediterranean, Levantine Arab, Iranian, and Sub-Saharan populations to the Emiratis' gene pool appears to be minor.

Indexed as

HLA-A AntigensGene FrequencyHumansIranPhylogenyUnited Arab EmiratesHLA-A AntigensalleleArabsEmiratisgenotypinghaplotypesHLAhuman leukocyte antigen

Identifiers

PMID37372339
PMCPMC10298278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.