Evidence map›Paper›PMID 37372046›Full record

ArticleBiology2023

Brain-Derived Estrogen Regulates Neurogenesis, Learning and Memory with Aging in Female Rats.

Yuanyuan Huang, Wuxiang Sun, Fujia Gao, Haoran Ma, Tao Yuan, Zixuan Liu, Huiyu Liu, Jiewei Hu, Jing Bai, Xin Zhang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Boosting Neurogenesis as a Strategy in Treating Alzheimer's Disease.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Yuanyuan HuangNeurobiology Institute, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Wuxiang SunNeurobiology Institute, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Fujia GaoNeurobiology Institute, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Haoran MaNeurobiology Institute, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Tao YuanNeurobiology Institute, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Zixuan LiuNeurobiology Institute, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Huiyu LiuNeurobiology Institute, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Jiewei HuNeurobiology Institute, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Jing BaiNeurobiology Institute, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Xin ZhangNeurobiology Institute, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
Ruimin WangNeurobiology Institute, School of Public Health, North China University of Science and Technology, Tangshan 063210, China.
North China University of Science and Technology · CN

Funding

National Natural Science Foundation of China 81671223Science and Technology Project of Hebei Education Department ZD2021087
6 · The paper itself

Abstract

Although 17β-estradiol (E2) can be locally synthesized in the brain, whether and how brain-derived E2 (BDE2) impacts neurogenesis with aging is largely unclear. In this study, we examined the hippocampal neural stem cells, neurogenesis, and gliogenesis of 1, 3, 6, 14, and 18-month (Mon) female rats. Female forebrain neuronal

Indexed as

agingaromatasebrain-derived estrogengliogenesisneurogenesis

Identifiers

PMID37372046
PMCPMC10295457
OpenAlexW4378078130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.