Evidence map›Paper›PMID 37372016›Full record

ReviewAntioxidants (Basel, Switzerland)2023

Therapeutic Applications of Plant-Derived Extracellular Vesicles as Antioxidants for Oxidative Stress-Related Diseases.

Manho Kim, Hyejun Jang, Wijin Kim, Doyeon Kim, Ju Hyun Park

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Two New Alkaloids and a Triterpenoid Glycoside fromAntioxidants (Basel, Switzerland) · 2026
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Manho KimDepartment of Biomedical Science, Kangwon National University, Chuncheon-si 24341, Republic of Korea.
Hyejun JangDepartment of Biomedical Science, Kangwon National University, Chuncheon-si 24341, Republic of Korea.
Wijin KimDepartment of Biomedical Science, Kangwon National University, Chuncheon-si 24341, Republic of Korea.
Doyeon KimDepartment of Biomedical Science, Kangwon National University, Chuncheon-si 24341, Republic of Korea.
Ju Hyun ParkDepartment of Biomedical Science, Kangwon National University, Chuncheon-si 24341, Republic of Korea.ORCID 0000-0001-8590-7442
Kangwon National University · KR

Funding

National Research Foundation of Korea 2021R1A2C1010865OTTOGI HAM TAIHO Foundation 23-2132156
6 · The paper itself

Abstract

Extracellular vesicles (EVs) composed of a lipid bilayer are released from various cell types, including animals, plants, and microorganisms, and serve as important mediators of cell-to-cell communication. EVs can perform a variety of biological functions through the delivery of bioactive molecules, such as nucleic acids, lipids, and proteins, and can also be utilized as carriers for drug delivery. However, the low productivity and high cost of mammalian-derived EVs (MDEVs) are major barriers to their practical clinical application where large-scale production is essential. Recently, there has been growing interest in plant-derived EVs (PDEVs) that can produce large amounts of electricity at a low cost. In particular, PDEVs contain plant-derived bioactive molecules such as antioxidants, which are used as therapeutic agents to treat various diseases. In this review, we discuss the composition and characteristics of PDEVs and the appropriate methods for their isolation. We also discuss the potential use of PDEVs containing various plant-derived antioxidants as replacements for conventional antioxidants.

Indexed as

antioxidantscarcinogenesischronic wound healingoxidative stressplant-derived extracellular vesicleskin aging

Identifiers

PMID37372016
PMCPMC10295733
OpenAlexW4380990301

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.