ArticleAntioxidants (Basel, Switzerland)2023
Hydrogen-Rich Water Ameliorates Metabolic Disorder via Modifying Gut Microbiota in Impaired Fasting Glucose Patients: A Randomized Controlled Study.
Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 20 citations in OpenAlex.
- Individual variability in hydrogen-producing microbes influences the response to hydrogen supplementation on sleep quality: a randomized, double-blind, placebo-controlled, parallel study.Scientific reports · 2026Trial
- The Effects of 8-Week Hydrogen-Rich Water Consumption on Appetite, Body Composition, Sleep Quality, and Circulating Glucagon-like Peptide-1 in Obese Men and Women (HYDRAPPET): A Randomized Controlled Trial.Medicina (Kaunas, Lithuania) · 2025Trial
- Effects of Hydrogen-Rich Water on Antioxidant Capacity, Immune Response, and Gut Microbiota in Juvenile Snakehead (Animals : an open access journal from MDPI · 2026Article
- Protective effects of hydrogen-rich water against acute lead-induced hepatic, renal, and testicular toxicity in rats.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Oligomeric ultranano hydrogen water improves flock uniformity, antioxidant capacity and intestinal health in growth phase layer-type chickens.Poultry science · 2026Article
- Molecular Hydrogen as a Regulator of Mitochondrial Quality Control and Metabolic Reprogramming.International journal of molecular sciences · 2026Review
- The effect of hydrogen-rich water interventions on lipid profiles in adults with overweight or obesity and associated metabolic disorders: a systematic review and meta-analysis of randomized controlled trials.Diabetology & metabolic syndrome · 2026Review
- Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application.MedComm · 2025Review
- Hydrogen-Rich Water Decreases Muscle Damage and Improves Power Endurance in Elite Athletes: A Randomized, Double-Blinded, Placebo-Controlled Trial.Journal of lifestyle medicine · 2025Article
- Oral Administration of Hydrogen-rich Water: Biomedical Activities, Potential Mechanisms, and Clinical Applications.Current pharmaceutical design · 2025Review
- Hydrogen gas (HFrontiers in pharmacology · 2025Article
- Hydrogen inhalation: A novel approach to alleviating allergic rhinitis symptoms by modulating nasal flora.The World Allergy Organization journal · 2024Article
- Effects of hydrogen-rich water on blood uric acid in patients with hyperuricemia: A randomized placebo-controlled trial.Heliyon · 2024Article
- The Effects of Hydrogen-Rich Water on Blood Lipid Profiles in Metabolic Disorders Clinical Trials: A Systematic Review and Meta-analysis.International journal of endocrinology and metabolism · 2024Article
- The endogenous hydrogen gas (HFrontiers in endocrinology · 2024Article
- The impact of hydrogen-rich water on liver enzyme levels in clinical populations: a comprehensive review and meta-analysis.Gastroenterology and hepatology from bed to bench · 2024Review
- Hydrogen: A Rising Star in Gas Medicine as a Mitochondria-Targeting Nutrient via Activating Keap1-Nrf2 Antioxidant System.Antioxidants (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 6 institutions in 2 countries.
Funding
Abstract
objectiveMolecular hydrogen (H
methodsSeventy-three patients with IFG were enrolled in a randomized, double-blind, placebo-controlled clinical study. These patients were assigned to receive either 1000 mL per day of HRW or placebo pure water (no H
resultsBoth pure water and HRW demonstrated a significant reduction in fasting blood glucose in IFG patients, with a significant difference between pure water and HRW after eight weeks. Among IFG patients with abnormal pre-experimental fatty liver, 62.5% (10/16) in the HRW group and 31.6% (6/19) in the pure water group achieved remission. Furthermore, 16S RNA analysis revealed HRW-modified gut microbiota dysbiosis in the fecal samples of IGF patients. Through Pearson correlation analysis, the differential gut microbiota obtained by 16S analysis was found to be highly correlated with nine metabolites.
conclusionH
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.