Evidence map›Paper›PMID 37371973›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Innovative Fibrous Materials Loaded with 5-Nitro-8-hydroxyquinoline via Electrospinning/Electrospraying Demonstrate Antioxidant, Antimicrobial and Anticancer Activities.

Mariya Spasova, Nikoleta Stoyanova, Nasko Nachev, Milena Ignatova, Nevena Manolova, Iliya Rashkov, Ani Georgieva, Reneta Toshkova, Nadya Markova

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mariya SpasovaLaboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Akad. G. Bonchev St, bl. 103A, BG-1113 Sofia, Bulgaria.ORCID 0000-0002-1603-4294
Nikoleta StoyanovaLaboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Akad. G. Bonchev St, bl. 103A, BG-1113 Sofia, Bulgaria.
Nasko NachevLaboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Akad. G. Bonchev St, bl. 103A, BG-1113 Sofia, Bulgaria.ORCID 0000-0003-2369-2057
Milena IgnatovaLaboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Akad. G. Bonchev St, bl. 103A, BG-1113 Sofia, Bulgaria.ORCID 0000-0003-2157-2537
Nevena ManolovaLaboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Akad. G. Bonchev St, bl. 103A, BG-1113 Sofia, Bulgaria.ORCID 0000-0001-8283-5340
Iliya RashkovLaboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Akad. G. Bonchev St, bl. 103A, BG-1113 Sofia, Bulgaria.ORCID 0000-0002-3965-3450
Ani GeorgievaInstitute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Akad. G. Bonchev St, bl. 25, BG-1113 Sofia, Bulgaria.
Reneta ToshkovaInstitute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Akad. G. Bonchev St, bl. 25, BG-1113 Sofia, Bulgaria.
Nadya MarkovaInstitute of Microbiology, Bulgarian Academy of Sciences, Akad. G. Bonchev St, bl. 26, BG-1113 Sofia, Bulgaria.

Funding

Bulgarian Science Fund KP-06-N39/13/2019
6 · The paper itself

Abstract

A new type of fibrous mat based on a cellulose derivative-cellulose acetate (CA) or CA and water-soluble polymers (polyvinylpyrrolidone, PVP or poly(vinyl alcohol), PVA)-loaded with the model drug 5-nitro-8-hydroxyquinoline (5N) was fabricated via electrospinning or electrospinning in conjunction with electrospraying. Scanning electron microscopy (SEM), X-ray diffraction analysis (XRD), Fourier-transform infrared spectroscopy (FTIR), water contact angle measurements and ultraviolet-visible spectroscopy (UV-Vis) were used for the complex characterization of the obtained novel material. The decoration of CA fibers with a water-soluble polymer containing the drug resulted in the facilitation of wetting and fast drug release. The 5N-containing fibrous material showed antioxidant activity. Moreover, the proposed materials' antibacterial and antifungal properties were tested against

Indexed as

5-nitro-8-hydroxyquinolineanticancer activitiesantimicrobialantioxidantcellulose acetateelectrospinningelectrosprayingwater-soluble polymer

Identifiers

PMID37371973
PMCPMC10295047

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.