Evidence map›Paper›PMID 37371963›Full record

ArticleAntioxidants (Basel, Switzerland)2023

The Impact of Alcohol Consumption and Oral Microbiota on Upper Aerodigestive Tract Carcinomas: A Pilot Study.

Marco Fiore, Antonio Minni, Luca Cavalcanti, Giammarco Raponi, Gianluca Puggioni, Alessandro Mattia, Sara Gariglio, Andrea Colizza, Piero Giuseppe Meliante, Federica Zoccali and 8 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Alcohol Consumption and Autoimmune Diseases.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Marco FioreInstitute of Biochemistry and Cell Biology (IBBC-CNR), Sapienza University Hospital Policlinico Umberto I, 00161 Roma, Italy.ORCID 0000-0001-6806-9715
Antonio MinniDepartment of Sensory Organs, Sapienza University of Rome, 00161 Roma, Italy.
Luca CavalcantiDepartment of Sensory Organs, Sapienza University of Rome, 00161 Roma, Italy.ORCID 0000-0002-3121-164X
Giammarco RaponiLaboratory for Clinical Microbiology, Sapienza University Hospital Policlinico Umberto I, 00161 Roma, Italy.ORCID 0000-0002-9665-0811
Gianluca PuggioniLaboratory for Clinical Microbiology, Sapienza University Hospital Policlinico Umberto I, 00161 Roma, Italy.
Alessandro MattiaDipartimento della Pubblica Sicurezza, Direzione Centrale di Sanità, Centro di Ricerche e Laboratorio di Tossicologia Forense, Ministero dell'Interno, 00185 Roma, Italy.ORCID 0000-0002-9051-4018
Sara GariglioDIFAR-Department of Pharmacy, Università di Genova, Viale Cembrano 4, 16148 Genova, Italy.ORCID 0000-0002-9507-8155
Andrea ColizzaDepartment of Sensory Organs, Sapienza University of Rome, 00161 Roma, Italy.ORCID 0000-0002-0639-806X
Piero Giuseppe MelianteDepartment of Sensory Organs, Sapienza University of Rome, 00161 Roma, Italy.ORCID 0000-0002-8762-3731
Federica ZoccaliDepartment of Sensory Organs, Sapienza University of Rome, 00161 Roma, Italy.ORCID 0000-0001-5481-4307
Luigi TaraniDepartment of Maternal Infantile and Urological Sciences, Sapienza University of Rome, 00161 Roma, Italy.ORCID 0000-0001-5958-9364
Christian BarbatoInstitute of Biochemistry and Cell Biology (IBBC-CNR), Sapienza University Hospital Policlinico Umberto I, 00161 Roma, Italy.ORCID 0000-0003-1737-9064
Marco LucarelliDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Roma, Italy.ORCID 0000-0002-5538-2494
Flavio Maria CeciDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Roma, Italy.ORCID 0000-0001-7744-218X
Silvia FrancatiDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Roma, Italy.
Giampiero FerragutiDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Roma, Italy.ORCID 0000-0001-6129-4071
Mauro CeccantiASL Roma1, SITAC, Società Italiana per il Trattamento dell'Alcolismo e le sue Complicanze, 00100 Roma, Italy.ORCID 0000-0001-9981-8715
Carla PetrellaInstitute of Biochemistry and Cell Biology (IBBC-CNR), Sapienza University Hospital Policlinico Umberto I, 00161 Roma, Italy.ORCID 0000-0003-0651-1816
Sapienza University of Rome · ITPoliclinico Umberto I · ITASL Roma · ITIstituto Pasteur · ITMinistry of Interior · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol consumption is associated with oxidative stress and an increased risk of carcinoma of the upper aero-digestive tract (UADT). Recently, it has been found that some microorganisms in the human oral cavity may locally metabolize ethanol, forming acetaldehyde, a carcinogenic metabolite of alcohol. In a cohort of patients first visited for UADT cancers, we estimated their alcohol consumption by measuring Ethyl Glucuronide/EtG (a long-lasting metabolite of ethanol) in the hair and carbohydrate-deficient transferrin/CDT (short-term index of alcohol intake) in the serum. Moreover, we analyzed, by culture-based methods, the presence of

Indexed as

ADH polymorphismalcoholhead and neck canceroral microbiotaoxidative stressROSupper aero-digestive tract cancer

Identifiers

PMID37371963
PMCPMC10295395
OpenAlexW4379875935

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.