Evidence map›Paper›PMID 37371944›Full record

ArticleAntioxidants (Basel, Switzerland)2023

The Influence of Melatonin Treatment in the Vinification of Feteasca Neagra and Cabernet Sauvignon Wines on the Profile of Polyphenolic Compounds and Antioxidant Activity.

Sandra A V Eremia, Camelia Albu, Gabriel-Lucian Radu, Andreia Alecu, Elena Brinduse

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Infrared Laser-Assisted Extraction of Bioactive Compounds fromInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sandra A V EremiaCentre of Bioanalysis, National Institute of Research and Development for Biological Sciences-Bucharest, 296 Splaiul Independentei, 060031 Bucharest, Romania.
Camelia AlbuCentre of Bioanalysis, National Institute of Research and Development for Biological Sciences-Bucharest, 296 Splaiul Independentei, 060031 Bucharest, Romania.ORCID 0000-0003-2481-8993
Gabriel-Lucian RaduCentre of Bioanalysis, National Institute of Research and Development for Biological Sciences-Bucharest, 296 Splaiul Independentei, 060031 Bucharest, Romania.ORCID 0000-0002-4385-1177
Andreia AlecuCentre of Bioanalysis, National Institute of Research and Development for Biological Sciences-Bucharest, 296 Splaiul Independentei, 060031 Bucharest, Romania.
Elena BrinduseInstitute for Research and Development for Viticulture and Wine Making, 2 Valea Mantei, Valea Calugareasca, 107620 Prahova, Romania.
National Institute of Research and Development for Biological Sciences · RO

Funding

Ministry of Research, Innovation and Digitization PN 7N/23-02-0101/2023Ministry of Research, Innovation and Digitization PN-III-P1-1.1-TE-2021-0321
6 · The paper itself

Abstract

Until recently, the main antioxidant role among wine constituents was attributed to polyphenolic compounds, but once the presence of melatonin in wines was confirmed, an interesting new field of research opened up due to its possible synergistic effects with other antioxidants in the winemaking process, which may lead to a change in the profile of polyphenolic compounds and antioxidant activity. In order to investigate the evolution of active principles from the phenylpropanoid metabolism associated with the synergistic effects of melatonin, for the first time, a melatonin treatment was performed in the pre-stage of the different winemaking processes of Feteasca Neagra and Cabernet Sauvignon wines with different melatonin concentrations. After comparing the acquired results for the evolution of the polyphenolic compound profile and antioxidant activity of treated wines, we ascertained an increase in the antioxidant compound concentrations, especially in resveratrol, quercetin, and cyanidin-3-glucoside, directly proportional to the used melatonin concentration; an intensification in activity of PAL and C4H enzymes; and the modification in the expression of specific anthocyanin biosynthesis genes, especially UDP-D-glucose-flavonoid-3-

Indexed as

antioxidant activityCabernet SauvignonFeteasca Neagramelatonin treatmentphenylpropanoid metabolismpolyphenolic compoundssynergistic effectswinemaking process

Identifiers

PMID37371944
PMCPMC10295522
OpenAlexW4379470678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.