Evidence map›Paper›PMID 37371864›Full record

ArticleBiomedicines2023

Risankizumab: Daily Practice Experience of High Need Patients.

Alexandra M G Brunasso, Martina Burlando, Fabrizio Amoruso, Luisa Arancio, Giovanna Malara, Raffaella Manzo, Maria Antonia Montesu, Giacomo Caldarola

Open access · goldAbstract readCase Reports
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Alexandra M G BrunassoDepartment of Internal Medicine, Villa Scassi Hospital ASL3, 16100 Genoa, Italy.ORCID 0000-0001-9122-9975
Martina BurlandoDepartment of Dermatology, Dipartimento di Scienze Della Salute, DISSAL, University of Genoa, 16100 Genoa, Italy.ORCID 0000-0002-4381-6718
Fabrizio AmorusoDermatology Unit, Azienda Ospedaliera di Cosenza, 87100 Cosenza, Italy.
Luisa ArancioUnit of Dermatology, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, 20019 Milan, Italy.
Giovanna MalaraUnità Operativa Complessa di Dermatologia, Azienda Ospedaliero-Universitaria, 89121 Reggio Calabria, Italy.
Raffaella ManzoU.O.C. Dermatologia, ASL Salerno Ospedale Tortora Pagani, 84121 Salerno, Italy.
Maria Antonia MontesuDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Giacomo CaldarolaUOC di Dermatologia, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli-IRCCS, 00118 Rome, Italy.ORCID 0000-0002-8837-9232
Azienda Ospedaliera di Cosenza · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITOspedale Policlinico San Martino · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Salerno · ITUniversity of Sassari · ITVilla Torri Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is a chronic inflammatory disease which affects 29.5 million people worldwide and it can negatively impact quality of life, especially when it affects a special localization, such as nails, face, palms and soles, or intertriginous regions. Risankizumab is a humanized monoclonal antibody which targets the p19 subunit of interleukin-23 and it is currently licensed also as systemic therapy for moderate to severe plaque psoriasis. Here, we present eight cases of patients with moderate to severe psoriasis treated with risankizumab with a significant efficacy in the remission of the disease. Our cases represent a real-world clinical setting and provide a valuable adjunct to results obtained in the selected patients usually included in controlled clinical trials. In our cases, risankizumab rapidly improved clinical manifestations and relieved symptoms in patients with moderate to severe psoriasis, regardless of the presence of comorbidities or the location of the plaques in special sites, and without any safety concerns.

Indexed as

monoclonal antibodypsoriasisrisankizumab

Identifiers

PMID37371864
PMCPMC10296177
OpenAlexW4381663176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.