Evidence map›Paper›PMID 37371814›Full record

ArticleBiomedicines2023

MicroRNAs Differentially Expressed in Actinic Keratosis and Healthy Skin Scrapings.

Maria Vincenza Chiantore, Marco Iuliano, Roberta Maria Mongiovì, Fabiola Luzi, Giorgio Mangino, Lorenzo Grimaldi, Luisa Accardi, Gianna Fiorucci, Giovanna Romeo, Paola Di Bonito

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Maria Vincenza ChiantoreEVOR Unit, Department of Infectious Diseases, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0001-5163-2698
Marco IulianoDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome-Polo Pontino, 04100 Latina, Italy.
Roberta Maria MongiovìDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome-Polo Pontino, 04100 Latina, Italy.
Fabiola LuziPlastic and Reconstructive Surgery, San Gallicano Dermatologic Institute IRCCS, 00144 Rome, Italy.
Giorgio ManginoDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome-Polo Pontino, 04100 Latina, Italy.ORCID 0000-0002-8950-9780
Lorenzo GrimaldiDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome-Polo Pontino, 04100 Latina, Italy.
Luisa AccardiEVOR Unit, Department of Infectious Diseases, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-5091-9272
Gianna FiorucciEVOR Unit, Department of Infectious Diseases, Istituto Superiore di Sanità, 00161 Rome, Italy.
Giovanna RomeoDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome-Polo Pontino, 04100 Latina, Italy.ORCID 0000-0002-7638-1001
Paola Di BonitoEVOR Unit, Department of Infectious Diseases, Istituto Superiore di Sanità, 00161 Rome, Italy.ORCID 0000-0002-4737-374X
Sapienza University of Rome · ITIstituto Superiore di Sanità · ITSan Gallicano Hospital · IT

Funding

Istituto Superiore di Sanità not applicableSapienza University of Rome Bando di Ateneo Sapienza-2020", Grant no. RM120172B8B7B997
6 · The paper itself

Abstract

Actinic keratosis (AK) is a carcinoma in situ precursor of cutaneous squamous cell carcinoma (cSCC), the second most common cancer affecting the Caucasian population. AK is frequently present in the sun-exposed skin of the elderly population, UV radiation being the main cause of this cancer, and other risk factors contributing to AK incidence. The dysregulation of microRNAs (miRNAs) observed in different cancers leads to an improper expression of miRNA targets involved in several cellular pathways. The TaqMan Array Human MicroRNA Card assay for miRNA expression profiling was performed in pooled AK compared to healthy skin scraping samples from the same patients. Forty-three miRNAs were modulated in the AK samples. The expression of miR-19b (

Indexed as

actinic keratosisbiomarkerscSCCmicroRNA

Identifiers

PMID37371814
PMCPMC10296342
OpenAlexW4380989080

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.